Nutrição e Epilepsia – Artigo 12
Neurobiochemical mechanisms of a ketogenic diet in refractory epilepsy
Abstract
A ketogenic diet is an important therapy used in the control of drug-refractory seizures. Many studies have shown that children and adolescents following ketogenic diets exhibit an over 50% reduction in seizure frequency, which is considered to be clinically relevant. These benefits are based on a diet containing high fat (approximately 90% fat) for 24 months. This dietary model was proposed in the 1920s and has produced variable clinical responses. Previous studies have shown that the mechanisms ...
Nutrição e Epilepsia – Artigo 11
Low Vitamin D Levels Are Common in Patients with Epilepsy
SUMMARY
Purpose—Vitamin D is important for bone health, and vitamin D deficiency may contribute to other disorders (e.g., autoimmune, infections, cancer, degenerative, diabetic, and vascular). Enzyme-inducing antiepileptic drugs have been particularly implicated for osteoporosis risk given their effects on vitamin D. We examined the prevalence of vitamin D deficiency in adult epilepsy patients.
Methods—We conducted an observational study of consecutive epilepsy patients treated by two clinicians at the Emory University ...
Nutrição e Epilepsia – Artigo 10
Long-term impact of the ketogenic diet on growth and resting energy expenditure in children with intractable epilepsy
Abstract
AIM—The long-term effects of the ketogenic diet, a high fat diet for treating intractable epilepsy, on resting energy expenditure (REE) are unknown. The aim of this study was to evaluate the impact of 15 months of ketogenic diet treatment on growth and REE in children with intractable epilepsy.
METHOD—Growth, body composition and REE were assessed at baseline, 3 and 15 months in 24 children (14 males, 10 females; mean age 5y 6mo (SD 26mo), range 7mo–6y ...
Nutrição e Epilepsia – Artigo 9
Ketogenic diet in children with intractable epilepsy: what about resting energy expenditure and growth?
The study by Groleau et al.1 looks at the effect of ketogenic diet treatment on resting energy expenditure (REE) and
growth in children with intractable epilepsy with and without cerebral palsy (CP) over 15 months. It is an attempt to
better understand the metabolic and nutritional long-term effects of the ketogenic diet in children at different degrees of risk for growth and body composition abnormalities.
Nutrição e Epilepsia – Artigo 8
High dose folic acid supplementation in women with epilepsy: Are we sure it is safe?
A B S T R A C T
Most experts agree that folic acid supplementation is a key preconception intervention, particularly in women with epilepsy who take anti-epileptic drugs (AEDs). Primary prevention of neural tube defect through folic acid supplementation results in reduction of risk in an otherwise healthy population. The current folic acid supplementation recommendation is that all women of childbearing potential be supplemented with at least 0.4 mg of folic acid daily prior to conception and during ...
Nutrição e Epilepsia – Artigo 7
Fish Oil Intake and Seizure Control in Children with Medically Resistant Epilepsy
Abstract
Background: There is considerable evidence which suggests that Omega 3 polyunsaturated fatty acids may have a potential use in the treatment of epilepsy.
Aim: The study was to investigate the effect of Omega 3 polyunsaturated fatty acids (as fi sh oil supplementation)
in reducing the frequency and severity of epileptic seizures in children with medically resistant epilepsy.
Materials and Methods: In the case-control study, a total of 70 children with medically resistant epilepsy underwent ...
Nutrição e Epilepsia – Artigo 6
Establishing an Adult Epilepsy Diet Center: Experience, efficacy and challenges
Ab s t r a c t
Article history:
Received 10 November 2015
Revised 25 February 2016
Accepted 26 February 2016
Available online 6 April 2016
Objectives: Over 250medical centers worldwide offer ketogenic diets to children with epilepsy; however, access to these therapies has been extremely limited for adults until recent years. We examine our 5-year experience creating and implementing a dedicated Adult Epilepsy Diet Center designed to provide adults with epilepsy access to ketogenic diets.
Material and ...
Nutrição e Epilepsia – Artigo 5
Epilepsy and recommendations for breastfeeding
A B S T R A C T
Purpose: The objective of this paper is to provide a synopsis of benefits and potential harmful effects of exposure to antiepileptic drugs (AEDs) via breastmilk, and present recommendations for breastfeeding in women with epilepsy.
Methods: The article is based on a discretionary selection of English language articles retrieved by a literature search in the PubMed database, the LactMed database, and the authors’ clinical experience.
Results: Breastfeeding is associated with benefits for the infant, including nutrition, ...
