Nutrição e Autismo – Artigo 20
Vitamin D, Neurosteroids and Autism
Summary
Vitamin D had been for a long time investigated for its effects on bone metabolism. Recently has been observed that the incidence of some neurodevelopmental disorders (including autism) increases hand in hand with vitamin D deficiency. Indeed, vitamin D was reported to modulate the biosynthesis of neurotransmitters and neurotrophic factors; moreover, its receptor was found in the central nervous system. Vitamin D deficiency was therefore assessed as a risk factor for autism, however the biological mechanism has not yet been revealed. In ...
Nutrição e Autismo – Artigo 19
Targeted Nutritional and Behavioral Feeding Intervention for a Child with Autism Spectrum Disorder
A variety of feeding issues and concerns, including food aversion, food selectivity, and complete food refusal, are not uncommon among children with autism spectrum disorder (ASD). Other underlying issues are often comorbid with the concerns for feeding and ASD. These may include food allergies, gastrointestinal issues, oral motor issues, and swallowing disorders. The refusal to consume particular foods coupled with the inability to tolerate, digest, and absorb these foods can compromise ...
Nutrição e Autismo – Artigo 18
Relative abundance of short chain and polyunsaturated fatty acids in propionic acid-induced autistic features in rat pups as potential markers in autism
Abstract
Background: Fatty acids are essential dietary nutrients, and one of their important roles is providing polyunsaturated fatty acids (PUFAs) for the growth and function of nervous tissue. Short chain fatty acids (SCFAs) are a group of compounds derived from the host microbiome that were recently linked to effects on the gut, the brain, and behavior. They are therefore linked to neurodevelopmental disorders such as autism. ...
Nutrição e Autismo – Artigo 17
Nutritional Status of Individuals with Autism Spectrum Disorders: Do We Know Enough?
ABSTRACT
The incidence of individuals with autism spectrum disorders (ASDs) is on the rise; therefore, well-timed screening is important. Given that this is a nutritionally vulnerable population, it is imperative to conduct a detailed nutritional assessment so that timely and intensive interventions can be recommended. This review article summarizes the research, focusing on the nutritional status of individuals with ASDs based on their nthropometric
measurements, biomarkers, and dietary assessmen...
Nutrição e Autismo – Artigo 16
Nutrition and Autism: Intervention Compared with Identification
I read with interest the paper by Ranjan and Nasser (1) reviewing nutritional status, biometrics, metabolic processes, and eating patterns in autistic children. Emphasis was placed on potential biomarkers to enable earlier diagnosis, with less attention on the potential of nutrition to prevent or modify the occurrence and expression of autism.
More research is needed in looking at the role of dietary FAs and antioxidants in the pathogenesis, as well as in the possible prevention of autistic phenotypic expression....
Nutrição e Autismo – Artigo 15
Nutrient Intake From Food in Children With Autism
Abstract
OBJECTIVE: The impact of abnormal feeding behaviors reported for children with autism spectrum disorders (ASDs) on their nutritional status is unknown. We compared nutrient intake from food consumed by children with and without ASD and examined nutrient deficiency and excess.
METHODS: Prospective 3-day food records and BMI for children (2–11 years) with ASD participating in the Autism Treatment Network (Arkansas, Cincinnati, Colorado, Pittsburgh, and Rochester) were compared with both the National Health and Nutrition ...
Nutrição e Autismo – Artigo 14
Neuron Membrane Trafficking and Protein Kinases Involved in Autism and ADHD
Abstract: A brain-enriched multi-domain scaffolding protein, neurobeachin has been identified as a candidate gene for autism patients. Mutations in the synaptic adhesion protein cell adhesion molecule 1 (CADM1) are also associated with autism spectrum disorder, a neurodevelopmental disorder of uncertain molecular origin. Potential roles of neurobeachin and CADM1 have been suggested to a function of vesicle transport in endosomal trafficking. It seems that protein kinase B (AKT) and cyclic adenosine monophos...
Nutrição e Autismo – Artigo 13
Neuroinflammation in Autism: Plausible Role of Maternal Inflammation, Dietary Omega 3, and Microbiota
Several genetic causes of autism spectrum disorder (ASD) have been identified. However, more recent work has highlighted that certain environmental exposures early in life may also account for some cases of autism. Environmental insults during pregnancy, such as infection or malnutrition, seem to dramatically impact brain development.Maternal viral or bacterial infections have been characterized as disruptors of brain shaping, even if their underlying mechanisms are not yet fully ...
