Nutrigenetics, epigenetics and gestational diabetes: consequences in mother and child
ABSTRACT
Gestational Diabetes Mellitus (GDM) is the most common metabolic condition during pregnancy and may result in short- and long-term complications for both mother and offspring. The complexity of phenotypic outcomes seems influenced by genetic susceptibility, nutrient-gene interactions and lifestyle interacting with clinical factors. There is strong evidence that not only the adverse genetic background but also the epigenetic modifications in response to nutritional and environmental factors ...
Comparison of Serum Levels of Vitamin D and Inflammatory Markers Between Women With Gestational Diabetes Mellitus and Healthy Pregnant Control
Abstract
Objective: Vitamin D appears to be involved in regulation of glycemic and inflammatory responses in gestational diabetes. The purpose of this study was to compare the serum levels of 25-hydroxyvitamin D (25(OH)D), inflammatory biomarkers and glycemic profile between gestational diabetes mellitus (GDM) and normal glucose tolerance (NGT) pregnant women.
Materials and methods: In this cross-sectional study, fasting serum levels of ...
Carbohydrate Content in the GDM Diet: Two Views View 1: Nutrition Therapy in Gestational Diabetes: The Case for Complex Carbohydrates
■ IN BRIEF Restriction of dietary carbohydrate has been the cornerstone for treatment of gestational diabetes mellitus (GDM). However, there is evidence that a balanced liberalization of complex carbohydrate as part of an overall eating plan in GDM meets treatment goals and may mitigate maternal adipose tissue insulin resistance, both of which may promote optimal metabolic outcomes for mother and offspring.
Medical nutrition therapy for gestational diabetes mellitus based on Mediterranean Diet principles: a subanalysis of the St Carlos GDM Prevention Study
Abstract
Objectives To assess whether Mediterranean Diet (MedDiet)-based medical nutrition therapy facilitates nearnormoglycemia in women with gestational diabetes mellitus (GDMw) and observe the effects on adverse pregnancy outcomes.
Research design and methods This is a secondary analysis of the St Carlos GDM Prevention Study, conducted
between January and December 2015 in Hospital Clínico San Carlos (Madrid, Spain). One ...
Combined diet and exercise interventions for preventing gestational diabetes mellitus (Review)
Background
Gestational diabetes mellitus (GDM) is associated with a wide range of adverse health consequences for women and their infants in the short and long term. With an increasing prevalence of GDM worldwide, there is an urgent need to assess strategies for GDM prevention, such as combined diet and exercise interventions. This is an update of a Cochrane review that was first published in 2015.
Objectives
To assess the effects of diet interventions in combination with exercise interve...
Relationship of Early Vitamin D Concentrations and Gestational Diabetes Mellitus in Indian Pregnant Women
Background: A high prevalence of vitamin D deficiency exists in pregnant Indian women (~90%). Increasing evidence suggests that vitamin D could play a pivotal role in maintaining normal glucose homeostasis. We aimed to determine the association between maternal vitamin D concentrations in early pregnancy and the risk of gestational diabetes mellitus (GDM).
Methods: A prospective observational study was conducted on healthy pregnant women (n = 392) attending routine antenatal care at ...
A High Adherence to Six Food Targets of the Mediterranean Diet in the Late First Trimester is
Associated with a Reduction in the Risk of Materno-Foetal Outcomes: The St. Carlos Gestational
Diabetes Mellitus Prevention Study
Abstract: A prenatal diet affects materno-foetal outcomes. This is a post hoc analysis of the St. Carlos gestational diabetes mellitus (GDM) Prevention Study. It aims to evaluate the effect of a late first-trimester (>12 gestational weeks) degree of adherence to a MedDiet pattern—based on six food targets—on a composite of materno-foetal outcomes (CMFCs). The ...
Medical nutrition therapy for gestational diabetes mellitus based on Mediterranean Diet principles: a subanalysis of the St Carlos GDM Prevention Study
Abstract
Objectives To assess whether Mediterranean Diet (MedDiet)-based medical nutrition therapy facilitates nearnormoglycemia in women with gestational diabetes mellitus (GDMw) and observe the effects on adverse pregnancy outcomes.
Research design and methods This is a secondary analysis of the St Carlos GDM Prevention Study, conducted
between January and December 2015 in Hospital Clínico San Carlos (Madrid, Spain). One ...
