Alimentando Práticas – Saúde Intestinal – Bruno Zylberg – livro 6
The Microbiota in Gastrointestinal Pathophysiology: Implications for Human Health, Prebiotics, Probiotics, and Dysbiosis
The modern history of the microbiota of the intestinal/gut microbiome is fascinating. The scientific world did not intensively develop its interest in this world of organisms until the national committee stimulated by Dr. Jeffrey Gordon published the paper Turnbaugh et€al. that clearly showed the microbiota of the gastrointestinal tract were numerous at approximately 1014 and, in effect, were more in number than cells in the human body [1]. With this ...
Alimentando Práticas – Saúde Intestinal – Bruno Zylberg – livro 4
The Human Microbiota and Chronic Disease: Dysbiosis as a Cause of Human Pathology
Conclusion
In conclusion, the gastrointestinal tract may be strongly affected by CF with a negative impact on nutritional status. CFTR dysfunction results in chronic inflammation and in an altered microbial composition in lung and intestine. Some evidence for the gut‐lung axis in CF comes from the link between intestinal microbiota and bacterial colonization of the respiratory tract. In addition, the effect of a restructure of intestinal microflora on intestinal inflammation and respiratory lung ...
Alimentando Práticas – Saúde Intestinal – Bruno Zylberg – livro 5
The Human Microbiota and Microbiome
Through the application of molecular and cellular microbiology, we now recognize the diversity and dominance of microbial life forms on our planet, which exist in all environments. These microbes have many important planetary roles, but for us humans a major problem is their ability to colonize our tissues and cause disease. The same techniques of molecular and cellular microbiology have been applied to the problems of human and animal infection during the past two decades and have proved to be immensely powerful tools in elucidating how microor...
Alimentando Práticas – Saúde Intestinal – Bruno Zylberg – livro 3
The Gut-Brain Axis Dietary, Probiotic, and Prebiotic Interventions on the Microbiota
Preface
Given the ever-increasing body of evidence that the gut, and more particularly the enteric microbiota, can affect central nervous system (CNS) function, it is perhaps not unsurprising that alterations in the microbiome, in many instances also accompanied by gut dysfunction, have been associated with significant CNS disorders. Some of these have their focus intuitively in the gut, such as obesity (chapter: Gut Microbiota and Metabolism) and irritable bowel syndrome (chapter: Dietary Interv...
Alimentando Práticas – Saúde Intestinal – Bruno Zylberg – livro 2
Microbiota of the Human Body: Implications in Health and Disease
Abstract
There are a range of methodologies available to study the human microbiota, ranging from traditional approaches such as culturing through to state-of-the-art developments in next generation DNA sequencing technologies. The advent of molecular techniques in particular has opened up tremendous new avenues for research, and has galvanised interest in the study of our microbial inhabitants. Given the dazzling array of available options, however, it is important to understand the inherent advantages and limit...
Alimentando Práticas – Saúde Intestinal – Bruno Zylberg – livro 1
Microbial Endocrinology: The Microbiota-Gut-Brain Axis inHealth and Disease
Abstract
Microbial endocrinology is defined as the study of the ability of microorganisms to both produce and recognize neurochemicals that originate either within the microorganisms themselves or within the host they inhabit. As such, microbial endocrinology represents the intersection of the fields of microbiology and neurobiology. The acquisition of neurochemical-based cell-to-cell signaling mechanisms in eukaryotic organisms is believed to have been acquired due to late horizontal gene transfer from ...
