Nutrição e Esteatose – Artigo 16
Effects of probiotics on nonalcoholic fatty liver disease: a systematic review and meta-analysis
AbstractBackground: Nonalcoholic fatty liver disease (NAFLD) has become prevalent in recent decades, especially in developed countries, and approaches for the prevention and treatment of NAFLD are not clear. The aim of this research was to analyze and summarize randomized controlled trials that investigated the effects of probiotics on NAFLD.Methods: Seven databases (PubMed, Embase, the Web of Science, the Cochrane Library, China National Knowledge Infrastructure, Wan Fang Data, and VIP ...
Nutrição e Esteatose – Artigo 15
Role of Probiotics in the Treatment of Nonalcoholic Fatty Liver Disease: A Meta-analysis
ABSTRACTAim: Despite extensive ongoing research, there is scarcity of widely accepted therapeutic options for the treatment of nonalcoholic fatty liver disease (NAFLD). Probiotics are a promising treatment option for treatingNAFLD; however, their effectiveness needs to be established. Since any single randomized controlled trial (RCT) cannot establish the role of probiotics in the treatment of NAFLD, this study aims at meta-analysis ofdifferent RCTs.Materials and methods: Extensive search was done by ...
Nutrição e Esteatose – Artigo 14
Probiotic mixture improves fatty liver disease by virtue of its action on lipid profiles, leptin, and inflammatory biomarkers
AbstractBackground: A high fat diet has an essential role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). This condition is characterized by hepatic fat accumulation (steatosis) and is associated with obesity, diabetes, and fibrosis or cirrhosis of the liver. Probiotics may be useful in the treatment of steatosis. This study examined the effects of an ingested probiotic formulation on the lipid profiles, liver functions, leptin levels, and ...
Nutrição e Esteatose – Artigo 13
Effect of probiotic supplementation in nonalcoholic steatohepatitis patients: PROBILIVER TRIAL protocol
AbstractBackground: Recently factors in the relationship between gut microbiota, obesity, diabetes and the metabolic syndrome have been suggested in the development and progression of nonalcoholic steatohepatitis (NASH). In this sense, this work aims to evaluate the effects of probiotic supplementation on intestinal microbiota modulation, degree of hepatic steatosis and fibrosis, inflammation, gut permeability, and body composition.Methods: This double-blind, randomized clinical trial ...
Nutrição e Esteatose – Artigo 12
Gut Microbiota and Nonalcoholic Fatty Liver Disease: Insights on Mechanisms and Therapy
Abstract: The gut microbiota plays critical roles in development of obese-related metabolic diseases such as nonalcoholic fatty liver disease (NAFLD), type 2 diabetes(T2D), and insulin resistance(IR), highlighting the potential of gut microbiota-targeted therapies in these diseases. There are various ways that gut microbiota can be manipulated, including through use of robiotics, prebiotics, synbiotics, antibiotics, and some active components from herbal medicines. In this review, we review the main ...
Nutrição e Esteatose – Artigo 11
Gut-Liver Axis, Nutrition, and Non Alcoholic Fatty Liver Disease
AbstractNonalcoholic fatty liver disease (NAFLD) represents a spectrum of diseases involving hepatic fat accumulation, inflammation with the potential progression to fibrosis and cirrhosis over time. NAFLD is often associated with obesity, insulin resistance, and diabetes. The interactions between the liver and the gut, the so-called ”gut-liver axis”, play a critical role in NAFLD onset and progression. Compelling evidence links the gut microbiome, intestinal barrier integrity, and NAFLD. The dietary factors may alter ...
Nutrição e Esteatose – Artigo 10
Nutrition, nonalcoholic fatty liver disease and the microbiome: recent progress in the field
AbstractPurpose of review—Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide and it has overlapping pathogenesis with diabetes and cardiovascular disease. Reviewed here are recent advances in understanding the contribution of diet and selectednutrients to NAFLD. Recent findings—To understand the effect of diet, the microbiome must be considered because it is the interface of diet and the liver. Early studies suggest that the characteristic of the ...
Nutrição e Esteatose – Artigo 9
Nutritional Approaches to Achieve Weight Loss in Nonalcoholic Fatty Liver Disease1–3
ABSTRACTNonalcoholic fatty liver disease (NAFLD) can range in spectrum from simple hepatic steatosis to nonalcoholic steatohepatitis (NASH), which ischaracterized by lipotoxicity, hepatocellular ballooning, and inflammation and can progress to cirrhosis. Weight loss is the cornerstone treatment for NAFLD and NASH. Various randomized controlled trials have shown that weight loss of $5–10% leads to significant improvements in hepatic steatosis. Diets high in sodium and fructose have been implicated in ...
