year : 2020 317 results

Nutrição e Esclerose Múltipla – Artigo 3

Impact of Nutritional Intake on Function in People with Mild-to-Moderate Multiple Sclerosis Background: We sought to assess the associations between nutrition and ambulation, daily activity, quality of life (QOL), and fatigue in individuals with mild-to-moderate disability with multiple sclerosis (MS). Methods: This cross-sectional pilot study included 20 ambulatory adult volunteers with MS (14 women and 6 men; mean ± SD age, 57.9 ± 10.2 years; mean ± SD Expanded Disability Status Scale score = 4.1 ± 1.8). Primary outcome variables included dietary assessment and the 6-Minute Walk ...

Nutrição e Esclerose Múltipla – Artigo 2

New Insights on the Nutrition Status and Antioxidant Capacity in Multiple Sclerosis Patients Abstract: Background: Multiple sclerosis (MS) is a multifactorial disease with unknown etiology. It is assumed to result from interplay between genetic and environmental factors, including nutrition. We hypothesized that there are differences in nutritional parameters between MS patients and healthy controls. Methods: We examined 63 MS patients and 83 healthy controls. Nutritional status was determined by a dietary questionnaire, blood tests, quantification of cell membrane fatty acids, and serum ...

Nutrição e Esclerose Múltipla – Artigo 1

Dietary Interventions and Multiple Sclerosis Abstract Multiple Sclerosis (MS) is a chronic, disabling neurologic disease that has its onset in young adulthood. While the knowledge about underlying pathogenesis of MS has improved significantly over the last few decades, the exact cause still eludes us. Despite the availability of several United States Food and Drug Administration-approved disease-modifying therapies (DMT) for MS in the last two decades, the disease remains disabling for many. DMT use is limited by its partial effectiveness, significant side effects in many cases, and high ...

Alimentando Práticas – Cronobiologia e sistema imunológico – Neiva Souza – Artigo 4

The mediating role of sleep, physical activity, and diet in the association between shift work and respiratory infections Objectives Shift work may be associated with an increased incidence of respiratory infections. However, underlying mechanisms are unclear. Therefore, our aim was to examine the mediating role of sleep, physical activity, and diet in the association between shift work and respiratory infections. Methods This prospective cohort study included 396 shift and non-shift workers employed in hospitals. At baseline, sleep duration and physical activity were measured using ...

Alimentando Práticas – Cronobiologia e sistema imunológico – Neiva Souza – Artigo 3

Sleep Loss as a Factor to Induce Cellular and Molecular Inflammatory Variations A reduction in the amount of time spent sleeping occurs chronically in modern society. Clinical and experimental studies in humans and animal models have shown that immune function is impaired when sleep loss is experienced. Sleep loss exerts a strong regulatory influence on peripheral levels of inflammatory mediators of the immune response. An increasing number of research projects support the existence of reciprocal regulation between sleep and low-intensity inflammatory response. Recent studies show that ...

Alimentando Práticas – Cronobiologia e sistema imunológico – Neiva Souza – Artigo 2

Rhythms of life: circadian disruption and brain disorders across the lifespan Abstract Many processes in the human body — including brain function — are regulated over the 24-hour cycle, and there are strong associations between disrupted circadian rhythms (for example, sleep–wake cycles) and disorders of the CNS. Brain disorders such as autism, depression and Parkinson disease typically develop at certain stages of life, and circadian rhythms are important during each stage of life for the regulation of processes that may influence the development of these disorders. Here, we ...

Alimentando Práticas – Cronobiologia e sistema imunológico – Neiva Souza – Artigo 1

Melatonin and Its Relation to the Immune System and Inflammation ABSTRACT: Melatonin (N -acetyl-5-methoxytryptamine) was initially thought to be produced exclusively in the pineal gland. Subsequently its synthesis was demonstrated in other organs, for example, the retinas, and very high concentrations of melatonin are found at other sites, for example, bone marrow cells and bile. The origin of the high level of melatonin in these locations has not been definitively established, but it is likely not exclusively of pineal origin. Melatonin has been shown to possess anti-inflammatory ...

Alimentando Práticas – Cronobiologia e sistema imunológico – Neiva Souza – slides

Neiva Souza Nutricionista. Doutoranda em Neurologia e Neurociências no Laboratório de Neurobiologia da Pineal. Pós-graduada em Nutrição Clínica Funcional, Fitoterapia Funcional e em Nutrição Esportiva Funcional pela Unicsul/VP. Docente do curso de pós-graduação em Nutrição Clínica Funcional e Fitoterapia Funcional da Unicsul/VP.