Nutrição e Distúrbios do Sono – Artigo 3
Perda de qualidade do sono e fatores associados em mulheres climatéricas
Resumo O objetivo deste artigo é identificar a prevalência de perda da qualidade do sono em mulheres climatéricas e os fatores associados. Estudo quantitativo, transversal e analítico, cujas variáveis foram investigadas por questionário estruturado/ pré-testado e pelo Índice de Qualidade do Sono de Pittsburgh, em 819 mulheres climatéricas assistidas pela Estratégia Saúde da Família. Regressão de Poisson simples foi utilizada para triagem das variáveis (p < 0, 25). Para a modelagem hierarquizada foi ...
Nutrição e Distúrbios do Sono – Artigo 2
Duração do sono, excesso de peso e consumo de alimentos ultraprocessados em adolescentes
Resumo
O objetivo deste artigo é analisar a relação entre duração insuficiente do sono, sobrepeso/ obesidade e o consumo de alimentos ultraprocessados em adolescentes de 10 a 14 anos. Trata-se de um estudo transversal, com avaliação de 1.384 adolescentes de escolas públicas de João Pessoa-PB, participantes do Estudo Longitudinal sobre Comportamento Sedentário, Atividade Física, Hábitos Alimentares e Saúde de Adolescentes (LONCAAFS). Foram mensuradas variáveis sociodemográficas, ...
Nutrição e Distúrbios do Sono – Artigo 1
Vitamin D Supplementation and Sleep: A Systematic Review and Meta-Analysis of Intervention Studies
Abstract: Background: Vitamin D deficiency is associated with sleep disorders and poor sleep quality. Whether vitamin D supplementation (VDS) helps resolve these problems remains unclear.
Objective: To systematically review the effect of VDS on sleep quantity, quality, and disorders, and perform a meta-analysis of available data.
Methods: The reporting of this review followed the PRISMA statement. VDS human interventions studies that reported on sleep quality, quantity, or disorders were ...
Discussão Científica – Autismo – Profª Denise Carreiro – Artigo 5
Peptides and Exorphins in the Autism Spectrum
Abstract
Problem: Some researchers have not found the opioids in urine of autistic children. We have therefore looked at this problem again.
Method: Mass spectrometry and fragmentation mass spectrometry (MS/MS) have been carried out on peaks from the HPLC that show co-chromatography with synthetic standards and peaks that are shared by different autistic children.
Results: In quickly frozen urine we find the presence of exorphins, and can also demonstrate a rather fast
break down at room temperature of these peptides in urine.
Conclusion: ...
Discussão Científica – Autismo – Profª Denise Carreiro – Artigo 4
GABA System Dysfunction in Autism and Related Disorders: From Synapse to Symptoms
Abstract
Autism Spectrum Disorders (ASDs) are neurodevelopmental syndromes characterised by repetitive behaviours and restricted interests, impairments in social behavior and relations, and in language and communication. These symptoms are also observed in a number of developmental disorders of known origin, including Fragile X Syndrome, Rett syndrome, and Fetal Anticonvulsant Syndrome. While these conditions have diverse etiologies, and poorly understood pathologies, emerging evidence suggests that they may ...
Discussão Científica – Autismo – Profª Denise Carreiro – Artigo 3
The Kynurenine Pathway As a Novel Link between Allergy and the Gut Microbiome
In the past few decades, the indoleamine 2,3 dioxygenase (IDO) subset of the kynurenine (KYN) pathway of tryptophan (TRP) metabolism has been the subject of much research in the area of immune tolerance. In this review, we aim to incorporate new findings on this pathway in relation to allergy and the gut microbiome, while providing a comprehensive overview of the pathway itself. Stimulated by interferon gamma, IDO acts as a tolerogenic, immunosuppressive enzyme to attenuate allergic responses by the induction of ...
Discussão Científica – Autismo – Profª Denise Carreiro – Artigo 2
Involvement of Neuroinflammation during Brain Development in Social Cognitive Deficits in Autism Spectrum Disorder and Schizophrenia
ABSTRACT
Development of social cognition, a unique and high-order function, depends on brain maturation from childhood to adulthood in humans. Autism spectrum disorder (ASD) and schizophrenia have similar social cognitive deficits, although age of onset in each disorder is different. Pathogenesis of these disorders is complex and contains several features, including genetic risk factors, environmental risk factors, and sites of abnormalities in the brain. ...
