• Nutrição e Sistema Imune – Artigo 4

    Immune Function and Micronutrient Requirements Change over the Life Course Abstract: As humans age, the risk and severity of infections vary in line with immune competence according to how the immune system develops, matures, and declines. Several factors influence the immune system and its competence, including nutrition. A bidirectional relationship among nutrition, infection and immunity exists: changes in one component affect the ...
  • Nutrição e Sistema Imune – Artigo 3

    Zinc Signals and Immunity Abstract: Zinc homeostasis is crucial for an adequate function of the immune system. Zinc deficiency as well as zinc excess result in severe disturbances in immune cell numbers and activities, which can result in increased susceptibility to infections and development of especially inflammatory diseases. This review focuses on the role of zinc in regulating intracellular signaling pathways in innate as well as ...
  • Nutrição e Sistema Imune – Artigo 2

    Zinc in Human Health: Effect of Zinc on Immune Cells Although the essentiality of zinc for plants and animals has been known for many decades, the essentiality of zinc for humans was recognized only 40 years ago in the Middle East. The zinc-deficient patients had severe immune dysfunctions, inasmuch as they died of intercurrent infections by the time they were 25 years of age. In our studies in an experimental human model of zinc deficie...
  • Nutrição e Sistema Imune – Artigo 1

    Zinc: dietary intake and impact of supplementation on immune function in elderly Abstract The diet in the elderly does not provide a sufficient level of nutrients needed to maintain an adequate healthy status leading to micronutrient deficiencies and impaired immune response with subsequent development of degenerative diseases. Nutrient “zinc” is a relevant micronutrient involved in maintaining a good integrity of many body ...
  • Nutrição e Diabetes Mellitus Gestacional – Artigo 23

    Polysaccharide IV from Lycium barbarum L. Improves Lipid Profiles of Gestational Diabetes Mellitus of Pregnancy by Upregulating ABCA1 and Downregulating Sterol Regulatory Element-Binding Transcription 1 via miR-33 Lycium barbarum L. (LBL) has beneficial effects on gestational diabetes mellitus (GDM) but the related mechanism remains unclear. Polysaccharides of LBL (LBLP) are the main bioactive components of LBL. miR-33, ATP-binding cassette ...
  • Nutrição e Diabetes Mellitus Gestacional – Artigo 22

    Higher maternal dietary protein intake is associated with a higher risk for gestational diabetes mellitus in a multi-ethnic Asian cohort Abstract Background—Dietary protein may affect glucose metabolism through several mechanisms, but results from studies on dietary protein intake and risk of gestational diabetes mellitus (GDM) have been inconsistent. Objective—We examined the cross-sectional associations of dietary protein intake ...
  • Nutrição e Diabetes Mellitus Gestacional – Artigo 21

    Dietary iron intake, iron status, and gestational diabetes ABSTRACT Pregnant women are particularly vulnerable to iron deficiency and related adverse pregnancy outcomes and, as such, are routinely recommended for iron supplementation. Emerging evidence from both animal and population-based studies, however, has raised potential concerns because significant associations have been observed between greater iron stores and disturbances in ...
  • Nutrição e Diabetes Mellitus Gestacional – Artigo 20

    Effects of probiotic supplements on insulin resistance in gestational diabetes mellitus: A double-blind randomized controlled trial ABSTRACT Aims/Introduction: To evaluate the effect of probiotic supplements on insulin resistance in pregnant women with diet-controlled gestational diabetes mellitus. Materials and Methods: A randomized, double-blind, placebo-controlled trial was carried out between June 2016 and February 2017. Pregnant ...