• Nutrição e Esteatose Hepática não alcoólica – Artigo 16

    Supplementation with Alpha-Tocopherol and Ascorbic Acid to Nonalcoholic Fatty Liver Disease’s Statin Therapy in Men Abstract Oxidative stress and inflammation contribute to the pathogenesis and progression of nonalcoholic fatty liver disease (NAFLD), and the control of lipid status by statins may help to stop the progression of NAFLD. We hypothesized that the addition of antioxidant vitamins C and E to atorvastatin therapy is associ...
  • Nutrição e Esteatose Hepática não alcoólica – Artigo 15

    Role of Probiotics in Non-alcoholic Fatty Liver Disease: Does Gut Microbiota Matter? Abstract: Non-alcoholic fatty liver disease (NAFLD) is the hepatic consequence of metabolic syndrome, which often also includes obesity, diabetes, and dyslipidemia. The connection between gut microbiota (GM) and NAFLD has attracted significant attention in recent years. Data has shown that GM affects hepatic lipid metabolism and influences the balance ...
  • Nutrição e Esteatose Hepática não alcoólica – Artigo 14

    Perfluoroalkyl substances and severity of nonalcoholic fatty liver in Children: An untargeted metabolomics approach ABSTRACT Background: Toxicant-associated steatohepatitis has been described in adults but less is known regarding the role of toxicants in liver disease of children. Perfluoroalkyl substances (PFAS) cause hepatic steatosis in rodents, but few previous studies have examined PFAS effects on severity of liver injury in childr...
  • Nutrição e Esteatose Hepática não alcoólica – Artigo 13

    Nonalcoholic Fatty Liver Disease and Insulin Resistance: New Insights and Potential New Treatments Abstract: Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver disorders worldwide. It is associated with clinical states such as obesity, insulin resistance, and type 2 diabetes, and covers a wide range of liver changes, ranging from simple steatosis to non-alcoholic steatohepatitis (NASH), liver cirrhosis, and ...
  • Nutrição e Esteatose Hepática não alcoólica – Artigo 12

    Nonalcoholic fatty liver disease and alcoholic liver disease: metabolic diseases with systemic manifestations Abstract: The progression of liver disease is portrayed by several common, overarching signs and symptoms. Classically, these include findings such as spider angiomata, jaundice, palmar erythema, and as cirrhosis decompensates, ascites, variceal hemorrhage (VH), hepatic encephalopathy (HE), and hepatocellular carcinoma (HCC). ...
  • Nutrição e Esteatose Hepática não alcoólica – Artigo 11

    Micronutrients in Nonalcoholic Fatty Liver Disease Pathogenesis SUMMARY We review the contribution of micronutrients to nonalcoholic fatty liver disease pathology and therapeutics. We examine the relevant data on minerals, vitamins, and carotenoids in nonalcoholic fatty liver disease experimental and human studies and offer insight into their use (or nonuse) therapeutically. Micronutrients include electrolytes, minerals, vitamins, ...
  • Nutrição e Esteatose Hepática não alcoólica – Artigo 10

    Lipid Modulating Anti-oxidant Stress Activity of Gastrodin on Nonalcoholic Fatty Liver Disease Larval Zebrafish Model Abstract: Non-alcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) is the most common chronic liver disease in the world. However, there are still no drugs for NAFLD/NASH in the market. Gastrodin (GAS) is a bioactive compound that is extracted from Gastrodia elata, which is used as an active ...
  • Nutrição e Esteatose Hepática não alcoólica – Artigo 9

    Gut Microbiota and Nonalcoholic Fatty Liver Disease: Insights on Mechanisms and Therapy Abstract: The gut microbiota plays critical roles in development of obese-related metabolic diseases such as nonalcoholic fatty liver disease (NAFLD), type 2 diabetes(T2D), and insulin resistance(IR), highlighting the potential of gut microbiota-targeted therapies in these diseases. There are various ways that gut microbiota can be manipulated, ...