• Nutrição e Fibromialgia – Artigo 1

    A low fermentable oligo-di-mono-saccharides and polyols (FODMAP) diet is a balanced therapy for fi bromyalgia with nutritional and symptomatic benefi ts Abstract Introduction: Fibromyalgia is a chronic rheumatic disease producing widespread pain, associated to a major comorbidity -irritable bowel syndrome. Low FODMAPS diet (low fermentable oligo-di-mono-saccharides and polyols diet) has been effective in controlling irritable bowel syn...
  • Nutrição e Envelhecimento – Artigo 20

    Vitamin D deficiency in older adults and its associated factors: a cross-sectional analysis of the Mexican Health and Aging Study Abstract Summary—Vitamin D deficiency was common in older adults from a country with adequate sun exposure. The variables associated with this deficiency provide insight into the next steps needed to characterize older adults with this deficiency and to treat it accordingly. Purpose—The aim of this study ...
  • Nutrição e Envelhecimento – Artigo 19

    Vitamin C, Aging and Alzheimer’s Disease Abstract: Accumulating evidence in mice models of accelerated senescence indicates a rescuing role of ascorbic acid in premature aging. Supplementation of ascorbic acid appeared to halt cell growth, oxidative stress, telomere attrition, disorganization of chromatin, and excessive secretion of inflammatory factors, and extend lifespan. Interestingly, ascorbic acid (AA) was also found to positively ...
  • Nutrição e Envelhecimento – Artigo 18

    Vitamin B12 deficiency and impaired expression of amnionless during aging Abstract Background: Physical frailty and loss of mobility in elderly individuals lead to reduced independence, quality of life, and increased mortality. Vitamin B12 deficiency has been linked to several age-related chronic diseases, including in the musculo-skeletal system, where vitamin B12 deficiency is generally believed to be linked to poor nutritional intake. ...
  • Nutrição e Envelhecimento – Artigo 17

    TOR-mediated regulation of metabolism in aging Summary Cellular metabolism is regulated by the mTOR kinase, a key component of the molecular nutrient sensor pathway that plays a central role in cellular survival and aging. The mTOR pathway promotes protein and lipid synthesis and inhibits autophagy, a process known for its contribution to longevity in several model organisms. The nutrient-sensing pathway is regulated at the lysosomal ...
  • Nutrição e Envelhecimento – Artigo 16

    The influence of vitamins E and C and exercise on brain aging Abstract Age-related declines in motor and cognitive function have been associated with increases in oxidative stress. Accordingly, interventions capable of reducing the oxidative burden would be capable of preventing or reducing functional declines occurring during aging. Popular interventions such as antioxidant intake and moderate exercise are often recommended to attain ...
  • Nutrição e Envelhecimento – Artigo 15

    Serum Tocopherol Levels and Vitamin E Intake are Associated with Lung Function in the Normative Aging Study Abstract Background and Aims—The results of studies assessing relationships between vitamin E intake and status and lung function are conflicting. This study aimed to evaluate the effect of vitamin E intake and serum levels of tocopherol isoforms on lung function in a cross-sectional sample of 580 men from the Normative Aging ...
  • Nutrição e Envelhecimento – Artigo 14

    Regulation of metabolic health and aging by nutrient-sensitive signaling pathways Abstract All organisms need to be capable of adapting to changes in the availability and composition of nutrients. Over 75 years ago, researchers discovered that a calorie restricted (CR) diet could significantly extend the lifespan of rats, and since then a CR diet has been shown to increase lifespan and healthspan in model organisms ranging from yeast to ...