Nutrição e Depressão – Artigo 4

Depression among people with type 2 diabetes mellitus, US National Health and Nutrition Examination Survey (NHANES), 2005–2012 Abstract Background: Depression in people with diabetes can result in increased risk for diabetes-related complications. The prevalence of depression has been estimated to be 17.6 % in people with type 2 diabetes mellitus (T2DM), based on studies published between 1980 and 2005. There is a lack of more recent ...

Nutrição e Depressão – Artigo 3

Decreased Prostaglandin D2 Levels in Major Depressive Disorder Are Associated with Depression- Like Behaviors Abstract Background: Prostaglandin (PG) D2 is the most abundant prostaglandin in the mammalian brain. The physiological and pharmacological actions of PGD2 in the central nervous system seem to be associated with some of the symptoms exhibited by patients with major depressive disorder. Previous studies have found that PGD2 ...

Nutrição e Depressão – Artigo 2

Complementary and Alternative Medicine Therapies for Perinatal Depression Abstract Complementary and Alternative Medicine (CAM) therapies are increasingly sought out by patients with psychiatric disorders. This article provides a review of the evidence for several commonly utilized CAM therapies (i.e. omega-3 fatty acids, folate, S-adenosyl-methionine (SAMe), St. John’s Wort, bright light therapy, exercise, massage, and acupuncture) in ...

Nutrição e Depressão – Artigo 1

A study on the relationship between compulsive exercise, depression and anxiety Background and aims: Exercise and physical activity are beneficial both physically and psychologically but a few individuals use exercise excessively resulting in physical and even psychological damage. There is evidence for bidirectional relationship between exercise with depression and anxiety showing that exercise can reduce anxiety and depression, whereas a ...

Nutrição e Disbiose – Artigo 19

Western diets, gut dysbiosis, and metabolic diseases: Are they linked? ABSTRACT Obesity afflicts 36.5% of the US population and 600 million individuals world-wide. Thus, it is imperative to understand the risk factors underlying metabolic disease including diet, activity level, sleep, and genetics. Another key contributory factor is the gut microbiota given its widely reported role in the development of metabolic disease. The gut microb...

Nutrição e Disbiose – Artigo 18

Vitamin D Deficiency Promotes Epithelial Barrier Dysfunction and Intestinal Inflammation Background. Vitamin D, an important modulator of the immune system, has been shown to protect mucosal barrier homeostasis. This study investigates the effects of vitamin D deficiency on infection-induced changes in intestinal epithelial barrier function in vitro and on Citrobacter rodentium–induced colitis in mice. Methods. Polarized epithelial ...

Nutrição e Disbiose – Artigo 17

Understanding the Representative Gut Microbiota Dysbiosis in Metformin-Treated Type 2 Diabetes Patients Using Genome-Scale Metabolic Modeling Dysbiosis in the gut microbiome composition may be promoted by therapeutic drugs such as metformin, the world’s most prescribed antidiabetic drug. Under metformin treatment, disturbances of the intestinal microbes lead to increased abundance of Escherichia spp., Akkermansia muciniphila, ...

Nutrição e Disbiose – Artigo 16

Transglutaminases in Dysbiosis As Potential Environmental Drivers of Autoimmunity Protein-glutamine g-glutamyltransferases (transglutaminases, Tgs) belong to the class of transferases. They catalyze the formation of an isopeptide bond between the acyl group at the end of the side chain of protein- or peptide-bound glutamine residues and the first order +-amine groups of protein- or peptide-bound lysine. The Tgs are considered to be ...