IMPACT OF STATIN THERAPY ON COLLAGEN TURNOVER AND LEFT VENTRICLE FUNCTION AFTER ST-ELEVATION MYOCARDIAL INFARCTION: A RANDOMIZED CLINICAL TRIAL
Background: Chronic statin treatment reduces extracellular proteolysis and extracellular matrix remodeling impacting in myocardial
functional and structural parameters. However, it remains unclear whether early statin use after myocardial infarction (MI) reduces leftventricular (LV) adverse remodel...
Impact of collagen hydrolysate in middle-aged athletes with knee and ankle osteochondral lesions:
ABSTRACT
Introduction: Osteochondral lesions (OCL) are a significant issue among professional and amateur athletes in several sports modalities. Lack of treatment or inadequate therapy may aggravate the symptoms and jeopardize the chance of a complete functional recovery. Multidisciplinary treatment is the mainstay of OCL, including physioth...
Efficacy of Oral Collagen in Joint Pain - Osteoarthritis and Rheumatoid Arthritis
Abstract
Introduction: Joint pain is one of the most common types of chronic pain. Osteoarthritis (OA) and rheumatoid arthritis (RA) are the two leading causes of joint pain and there are currently no prophylactic or curative treatments available. Oral collagen has been implicated in providing a potential means to treat arthritis. This review article aims to ...
The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials
Background Skin dryness and an accelerated fragmentation of the collagen network in the dermis are hallmarks of skin aging. Nutrition is a key factor influencing skin health and consequently its appearance. A wide range of dietary supplements is offered to ...
Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study
Abstract
Background: Undenatured type II collagen (UC-II) is a nutritional supplement derived from chicken sternum cartilage. The purpose of this study was to evaluate the efficacy and tolerability of UC-II for knee osteoarthritis (OA) pain and associated symptoms ...
Effect of enzymatically cross-linked tilapia scale collagen for osteoblastic differentiation of human mesenchymal stem cells
Abstract
Type I collagen is an abundant component of bone tissue that has been used for bone tissue engineering using various cross-linking methods, including chemical agents, ultraviolet irradiation, and dehydrothermal treatment to enhance its physical properties. Collagens derived from mammalian animals are generally ...
Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology
ABSTRACT In this double-blind, placebo-controlled clinical study, we investigated the efficacy of specific bioactive
collagen peptides (BCP) on the cellulite treatment of normal and overweight women. In total, 105 women aged 24–50 years
with moderate cellulite were randomized to orally receive a daily dosage of ...
Daily oral consumption of hydrolyzed type 1 collagen is chondroprotective and antiinflammatory in murine posttraumatic osteoarthritis
Abstract
Osteoarthritis (OA) is a degenerative joint disease for which there are no disease modifying therapies. Thus, strategies that offer chondroprotective or regenerative capability represent a critical unmet need. Recently, oral consumption of a hydrolyzed type 1 collagen (hCol1) preparation has been ...
