Insecticide Use and Breast Cancer Risk among Farmers’ Wives in the Agricultural Health Study
BACKGROUND: Some epidemiologic and laboratory studies suggest that insecticides are related to increased breast cancer risk, but the evidence is
inconsistent. Women engaged in agricultural work or who reside in agricultural areas may experience appreciable exposures to a wide range of
insecticides.
OBJECTIVE: We examined associations between insecticide use and breast cancer incidence among wives ...
A Systems Biology Approach Reveals Converging Molecular Mechanisms
that Link Different POPs to Common Metabolic Diseases
A number of epidemiological studies have identified statistical associations between
persistent organic pollutants (POPs) and metabolic diseases, but testable hypotheses regarding underlying molecular mechanisms to explain these linkages have not been published.
Objectives: We assessed the underlying mechanisms of POPs that have been associated with metabolic diseases; ...
Synergistic Effects of Heavy Metals and Pesticides in Living Systems
There is a widespread repeated exposure of the population to the pesticides and
heavy metals of occupational and environmental origin. Such population is forced to
undergo continuous stress imposed by combined exposure of the heavy metals and
different classes of the pesticides used in agricultural as well as health practices. The
existing reports from several workers have indicated that heavy metals and pesticides
in ...
Exposure to organophosphorus and organochlorine pesticides, perfluoroalkyl substances, and polychlorinated biphenyls in pregnancy and the association with impaired glucose tolerance and gestational diabetes mellitus: The MIREC Study
Background: Studies report increases in rates of gestational diabetes mellitus (GDM) over recent decades. Environmental chemicals may increase the risk of diabetes through impacts on glucose metabolism, mitochondrial dysfunction, and endocrine-disrupting ...
Inulin Supplementation Lowered the Metabolic Defects of Prolonged Exposure to Chlorpyrifos from Gestation to Young Adult Stage in Offspring Rats
Increasing evidence indicates that chlorpyrifos (CPF), an organophosphorus insecticide, is involved in metabolic disorders. We assess the hypothesis whether supplementation with prebiotics from gestation to adulthood, through a modulation of microbiota composition and fermentative activity, alleviates CPF induced metabolic disorders of 60 days old ...
Early-life chemical exposures and risk of metabolic syndrome
The global prevalence of obesity has been increasing at a staggering pace, with few
indications of any decline, and is now one of the major public health challenges worldwide. While obesity and metabolic syndrome (MetS) have historically thought to be largely driven by increased caloric intake and lack of exercise, this is insufficient to account for the observed changes in disease trends. There is now increasing evidence to suggest ...
The Effect of Exposure to Persistent Organic Pollutants on Metabolic Health among KOREAN Children during a 1-Year Follow-Up
Previous evidence suggests the potential for adverse effects of persistent organic pollutants (POPs) on metabolic health even at low-dose exposure levels common among the general population, but there is less evidence of these associations among children. Therefore, as part of a prospective cohort study, 214 children were measured for POPs exposure. After the 1-year ...
Human health implications of organic food and organic agriculture: a comprehensive review
This review summarises existing evidence on the impact of organic food on human health. It compares organic vs. conventional food production with respect to parameters important to human health and discusses the potential impact of organic management practices with an emphasis on EU conditions. Organic food consumption may reduce the risk of allergic disease and of overweight and obesity, but the ...
