Complicated urinary tract infection in adults
BACKGROUND:Complicated urinary tract infection occurs in individuals with functional or structural abnormalities of the genitourinary tract.
OBJECTIVE: To review current knowledge relevant to complicated urinary tract infection, and to provide evidence-based recommendations for management.
METHODS: The literature was reviewed through a PubMed search, and additional articles were identified by journal reference review. A draft guideline was ...
An introduction to the epidemiology and burden of urinary tract infections
Abstract: Urinary tract infections (UTIs) are the most common outpatient infections, with a lifetime incidence of 50−60% in adult women. This is a narrative review aimed at acting as an introduction to the epidemiology and burden of UTIs. This review is based on relevant literature according to the experience and expertise of the authors. The prevalence of UTI increases with age, and in women aged over 65 is ...
Anatomy and Physiology of the Urinary Tract: Relation to Host Defense and Microbial Infection
Abstract
The urinary tract exits to a body surface area that is densely populated by a wide range of microbes. Yet, under most normal circumstances, it is typically considered sterile, i.e., devoid of microbes, a stark contrast to the gastrointestinal and upper respiratory tracts where many commensal and pathogenic microbes call home. Not surprisingly, infection of the urinary tract over a healthy ...
Urinary tract infections in adult general practice patients
SUMMARY
Urinary tract infections (UTIs) are symptomatic infections of the urinary tract, mainly caused by the bacterium Escherichia coli. One in two women suffers from a UTI at least once in her life. The young and sexually active are particularly affected, but it is also seen in elderly, postmenopausal women. The likelihood of recurrence is high. Diagnosis is made with regard to typical complaints and the presence of leucocytes ...
Recent advances in recurrent urinary tract infection from pathogenesis and biomarkers to prevention
Abstract
Recurrent urinary tract infection (UTI) might be one of the most common problems in urological clinics. Recent research has revealed novel evidence about recurrent UTI and it should be considered a different disease from the first infection. The pathogenesis of recurrent UTI might include two mechanisms, bacterial factors and deficiencies in host defense. Bacterial survival in the ...
Urinary Tract Infection: Pathogenesis and Outlook
Abstract
The clinical syndromes comprising urinary tract infection (UTI) continue to exert significant impact on millions of patients worldwide, most of whom are otherwise healthy women. Antibiotic therapy for acute cystitis does not prevent recurrences, which plague up to one fourth of women after an initial UTI. Rising antimicrobial resistance among uropathogenic bacteria further complicates therapeutic decisions, necessitating new ...
CMEArticleUrinary tract infections in adults
Yvonne, a successful 26-year-old executive, went to your clinic for dysuria, urinary frequency and urinary urgency of two days’ duration. She had just returned from her honeymoon in Spain. She had no chronic diseases or prior surgical history and was not recently on antibiotics. This was the first time she experienced such symptoms. You performed urine dipstick analysis for her and confirmed the diagnosis of simple cystitis.
Urinary tract infections: epidemiology, mechanisms of infection and treatment options
Abstract
Urinary tract infections (UTIs) are a severe public health problem and are caused by a range of pathogens, but most commonly by Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Enterococcus faecalis and Staphylococcus saprophyticus. High recurrence rates and increasing antimicrobial resistance among uropathogens threaten to greatly increase the economic burden of these infections. In ...
