Nutrição e Saúde Cardiovascular – Artigo 13
Long-Term Immunomodulatory Effects of a
Mediterranean Diet in Adults at High Risk
of Cardiovascular Disease in the PREvencion´
con DIeta MEDiterranea (PREDIMED) ´
Randomized Controlled Trial1–3
Background: The Mediterranean diet (MedDiet) has demonstrated short-term anti-inflammatory effects, but little is known about its long-term immunomodulatory properties. Objective: Our goal was to assess the long-term effects of the MedDiet on inflammatory markers related to atherogenesis in adults at high risk of cardiovascular disease (CVD) compared with the effects of a low-fat diet (LFD). ...
Nutrição e Restrição de Sono – Artigo 1
The effects of Jiao-Tai-Wan on sleep, inflammation and insulin resistance in obesity-resistant rats with chronic partial sleep deprivation
Background: Jiao-Tai-Wan (JTW), composed of Rhizome Coptidis and Cortex Cinnamomi, is a classical traditional Chinese prescription for treating insomnia. Several in vivo studies have concluded that JTW could exert its therapeutical effect in insomnia rats. However, the specific mechanism is still unclear. The present study aimed to explore the effect of JTW on sleep in obesity-resistant (OR) rats with chronic partial sleep deprivation (PSD) and to clarify ...
Nutrição e sistema imunológico – Artigo 04
Effect of n-3 fatty acids on the expression
of inflammatory genes in THP-1
macrophages
Background: Uncontrolled inflammation participates in the development of inflammatory diseases. Beneficial effects of polyunsaturated fatty acids belonging to the n-3 family such as eicosapentaenoic acid (EPA) and
docosahexaenoic acid (DHA) on inflammation have been reported.
The present study investigates the basal effects of EPA, DHA and a mixture EPA + DHA on the expression of 10 genes (AKT1, MAPK, NFKB, TNFA, IL1Β, MCP1, ALOX5, PTGS2, MGST1and NOS2) related to inflammation in unstimulated cul...
