The pleiotropic role of vitamin A in regulating mucosal immunity
The effect of vitamin A on mucosal immunity has never been subjected to extensive studies until recently. We started to work in this area in
the early 1970s when we observed that children with protein-calorie malnutrition (PCM) often had defective mucosal immunity, judging from
the incidence of respiratory tract infections and diarrhea. We reported that these children had depressed secretory IgA (sIgA) levels in their
nasal wash fluids. The IgA level in specimens collected from those superimposed with some degrees ...
