Nutrição e Depressão – Artigo 16
The Effects of High-fat-diet Combined with Chronic Unpredictable Mild Stress on Depression-like Behavior and Leptin/LepRb in Male Rats
Obesity is a condition characterized by massive adipose tissue accumulation, which is usually caused by complicated
genetic and environmental factors1–3. Obesity is associated with many health problems including metabolic
syndrome, cardiovascular diseases and psychiatric disorders4–7. Depression is a major psychiatric disorder that
is characterized by low mood, anhedonia and cognitive impairment8,9. Clinical and epidemiological data suggest
that ...
Nutrição e Depressão – Artigo 15
Suppression of Neuroinflammatory and Apoptotic Signaling Cascade by curcumin Alone and in Combination with Piperine in Rat Model of Olfactory
Bulbectomy Induced Depression
Objectives: Bilateral destruction of the olfactory bulbs is known to cause behavioral changes analogous to symptoms of depression. Curcumin, a traditional Indian spice is currently being investigated in different psychiatric problems including depression. Dietary phytochemicals are currently used as an adjuvant therapy to accelerate their therapeutic efficacy. Therefore, the present study is an attempt to elucidate ...
Nutrição e Depressão – Artigo 14
Oxidative stress predicts depressive symptom changes with omega-3
fatty acid treatment in coronary artery disease patients
Background: Antidepressant efficacy of omega-3 polyunsaturated fatty acid (n-3 PUFA) treatment in coronary artery disease (CAD) patients remains unpredictable. N-3 PUFA can mitigate oxidative stress, which is common in CAD and may contribute to depressive symptoms. This study investigated whether greater pre-treatment oxidative stress, measured by the ratios of late-stage lipid peroxidation markers
(malondialdehyde [MDA], 4-hydroxy-2-nonenal [4-HNE], and 8-isopros...
Nutrição e Depressão – Artigo 13
Optimal Serum Selenium Concentrations Are Associated with Lower Depressive Symptoms and Negative Mood among Young Adults
Background: There is evidence that low, and possibly high, selenium status is associated with depressed mood. More evidence is needed to determine whether this pattern occurs in young adults with a wide range of serum concentrations of selenium.
Objective: The aim of this study was to determine if serum selenium concentration is associated with depressive symptoms and daily mood states in young adults.
Methods: A total of 978 young adults (aged 17–25 y) completed ...
Nutrição e Depressão – Artigo 12
Omega-3 Fatty Acids, Depressive Symptoms, and Cognitive
Performance in Patients With Coronary Artery Disease
Abstract: This trial investigated the efficacy of omega-3 polyunsaturated fatty acid (n-3 PUFA) treatment for improving depressive symptoms and cognitive performance in patients with coronary artery disease (CAD) participating in cardiac rehabilitation. Patients with CAD aged 45 to 80 years were randomized to receive either 1.9-g/d n-3 PUFA treatment or placebo for 12 weeks. Depressive symptoms were measured using the Hamilton Depression Rating Scale (HAM-D, primary outcome) ...
Nutrição e Depressão – Artigo 11
Long Chain Omega-3 Polyunsaturated Fatty Acid Supplementation Alleviates Doxorubicin-Induced Depressive-Like Behaviors and Neurotoxicity
in Rats: Involvement of Oxidative Stress and Neuroinflammation
Abstract: Doxorubicin (DOX) is a chemotherapeutic agent widely used in human malignancies. Its long-term use can cause neurobiological side-effects associated with depression. Omega-3 polyunsaturated fatty acids (!-3 PUFAs), the essential fatty acids found in fish oil, possess
neuroprotecitve and antidepressant activities. Thus, the aim of this study was to explore the potential protec...
Nutrição e Depressão – Artigo 10
High glycemic index diet as a risk factor for depression: analyses from
the Women’s Health Initiative
Background: The consumption of sweetened beverages, refined foods, and pastries has been shown to be associated with an increased
risk of depression in longitudinal studies. However, any influence that refined carbohydrates has on mood could be commensurate
with their proportion in the overall diet; studies are therefore needed that measure overall intakes of carbohydrate and sugar,
glycemic index (GI), and glycemic load.
Objective: We hypothesized that higher dietary GI and ...
Nutrição e Depressão – Artigo 9
Healthy and Unhealthy Dietary Patterns Are Related to Depression: A Case-Control Study
ObjectiveaaMajor depressive disorder is the leading cause of disability around the world. The relationship between depression and dietary patterns has been reported in a few studies but with controversial results. This study aimed to investigate this relationship in an Iranian population.
MethodsaaIn our study, 330 depressed patients (cases) and healthy people (controls) (1:2) were individually matched according to age, sex and area of residence. New cases of depression were recruited from two psychiat...
