Chá verde e efeitos à saúde – Artigo 20
White tea (Camellia sinensis) inhibits proliferation of the colon cancer cell
line, HT-29, activates caspases and protects DNA of normal cells against
oxidative damage
Tea (Camellia sinensis) is one of the most consumed beverages in the world. White tea is made from the buds and young leaves of the tea plant which are steamed and dried, whilst undergoing minimal oxidation. The MTT assay was used to test the extract on the effect of the proliferation of the colorectal cancer cell line, HT-29. The extract inhibited the proliferation of HT-29 cells with an IC50 of 87 lg/ml. The
extract ...
Chá verde e efeitos à saúde – Artigo 19
The safety of green tea extract supplementation in postmenopausal women at risk for breast cancer: results of the Minnesota Green Tea Trial
Green tea is one of the world’s most popular beverages and has been associated with a number of health benefits, including prevention of obesity (Huang et al. 2014), cardiovascular disease (Hodgson and Croft 2010), neurodegenerative diseases (Andrade and Assuncao 2012), and several site-specific cancers, including breast cancer (Yuan 2013). These beneficial effects are primarily attributed to the chemical properties of tea catechins, of which (-)-epi...
Chá verde e efeitos à saúde – Artigo 18
The Natural Polyphenol Epigallocatechin Gallate Protects Intervertebral Disc Cells from Oxidative Stress
Oxidative stress-related phenotypic changes and a decline in the number of viable cells are crucial contributors to intervertebral
disc degeneration. The polyphenol epigallocatechin 3-gallate (EGCG) can interfere with painful disc degeneration by reducing
inflammation, catabolism, and pain. In this study, we hypothesized that EGCG furthermore protects against senescence and/or cell
death, induced by oxidative stress. Sublethal and lethal oxidative stress were induced in primary human ...
Chá verde e efeitos à saúde – Artigo 17
Preventive Effects of a Major Component of Green Tea, Epigallocathechin-3-Gallate, on Hepatitis-B Virus DNA Replication
Background: Hepatitis B virus infection is one of the major world health problems. Epigallocatechin-3 gallate is the major component of the polyphenolic fraction of green tea and it has an anti-viral, anti-mutagenic, antitumorigenic, anti-angiogenic, anti-proliferative, and/or pro-apoptotic effects on mammalian cells. In this study, our aim was to investigate the inhibition of HBV replication by epigallocatechin-3 gallate in the Hep3B2.1-7 hepatocellular carcinoma ...
Chá verde e efeitos à saúde – Artigo 16
Preparation of catechin extracts and nanoemulsions from green tea leaf waste and their inhibition effect on prostate cancer cell PC-3
Green tea is one of the most commonly consumed natural health beverages in Taiwan’s market, with the major functional component catechin being shown to possess several biological activities such as antioxidation, anticancer, and prevention of cardiovascular disease. The objectives of this study were to develop a high-performance liquid chromatography–mass spectrometry method to determine the variety and content of catechins in green tea leaf waste, a ...
Chá verde e efeitos à saúde – Artigo 15
Oral epigallocatechin-3-gallate for treatment of dystrophic epidermolysis bullosa: a multicentre, randomized, crossover, double-blind, placebo-controlled clinical trial
Recessive dystrophic epidermolysis bullosa (RDEB) is a rare genodermatosis with severe blistering. No curative treatment is available. Scientific data indicated that epigallocatechin-3-gallate (EGCG), a green tea extract, might improve the phenotype of RDEB patients. In a multicentre, randomized, crossover, double-blind, placebocontrolled clinical trial, we evaluated a 4-month oral EGCG treatment regimen in 17 RDEB ...
Chá verde e efeitos à saúde – Artigo 14
Mechanisms of Body Weight Reduction and Metabolic Syndrome Alleviation by Tea
Tea, a popular beverage made from leaves of the plant Camellia sinensis, has been shown to reduce body weight, alleviate metabolic syndrome, and prevent diabetes and cardiovascular diseases in animal models and humans. Such beneficial effects have generally been observed in most human studies when the level of tea consumption was 3 to 4 cups (600–900 mg tea catechins) or more per day. Green tea is more effective than black tea. In spite of numerous studies, the fundamental mechanisms for these actions still ...
Chá verde e efeitos à saúde – Artigo 13
Mate and Tea Intake, Dietary Antioxidants and Risk of Breast Cancer: a Case-Control Study
Recently, we reported an inverse association between high ‘mate’ intake (infusion of Ilex paraguariensis herb, a staple beverage in temperate South America) and breast cancer (BC) risk. Stronger inverse associations were found in high strata of tea, vegetable, fruit and energy intakes, and in overweight/obese women, suggesting possible roles for ‘mate’ mainly from its antioxidant contribution. The present study attempted to thoroughly explore possible associations among ‘mate’ and tea ...
