Nutrição e Saúde Hepática – Artigo 15
The Role of Morbid Obesity in the Promotion of Metabolic Disruptions and Non-Alcoholic Steatohepatitis by Helicobacter Pylori
Background Helicobacter pylory (HP) infection has been associated to an increased rate of type 2 diabetes (T2D) and liver disease through its effect on insulin resistance and systemic inflammation. However, results are inconstant and no studies exist in morbidly obese patients, in which both insulin resistance and inflammation coexist. Material and Methods Cross-sectional study to evaluate the relationship between HP infection and alterations in carbohydrate metabol...
Nutrição e Saúde Hepática – Artigo 14
Tomato Juice Consumption Modifies the Urinary Peptide Profile in Sprague-Dawley Rats with Induced Hepatic Steatosis
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder in Western countries, with a high prevalence, and has been shown to increase the risk of type 2 diabetes, cardiovascular disease (CVD), etc. Tomato products contain several natural antioxidants, including lycopene—which has displayed a preventive effect on the development of steatosis and CVD. Accordingly, the aim of the present work was to evaluate the effect of tomato juice consumption on the ...
Nutrição e Saúde Hepática – Artigo 13
Vitamin B6 Prevents Endothelial Dysfunction, Insulin Resistance, and Hepatic Lipid Accumulation in Apoe−/− Mice Fed with High-Fat Diet
VitB6 deficiency has been associated with a number of adverse health effects. However, the effects of VitB6 in metabolic syndrome are poorly understood. Methods. VitB6 (50 mg/kg/day) was given to −/− mice with hkdigh-fat diet (HFD) for 8 weeks. Endothelial dysfunction, insulin resistance, and hepatic lipid contents were determined. Results. VitB6 administration remarkably increased acetylcholine-induced endothelium-dependent relaxation and decreased ...
Nutrição e Saúde Hepática – Artigo 11
Inflammation, mitochondrial metabolism and nutrition: the multi-faceted progression of non-alcoholic fatty liver disease to hepatocellular carcinoma
When ectopic accumulation of fat in the liver is accompanied by cell death, inflammation and mitochondrial dysfunction, liver cells may switch from normal growth to an out-ofcontrol state. One third of the population is now suffering NAFLD but estimates increase considerably in patients with consequences from comfortable lifestyles (1). This is because excessive food intake is currently responsible for the alarming increase in NAFLD prevalence ...
Diabetes e nutrição – Artigo 20
Paradigm Shifts in Nutrition Therapy for Type 2 Diabetes – Nutrition Therapy for Diabetes.
Nutrition therapy is the initial treatment for diabetes. However, recommended nutrition therapies tend to be largely based on consensus among experts rather than on scientific evidence. The principles of nutrition therapy in Japan have been inherited from the pioneers of diabetes research, but they lack current updates reflecting advances in nutrition science. Nutrition science is a constantly advancing field, just like other fields of science, and the accepted knowledge base changes over time. This ...
Diabetes e nutrição – Artigo 19
Dietary polyunsaturated fatty acids and their metabolites: Implications for diabetes pathophysiology, prevention, and treatment
In 2013, the global burden of diabetes was estimated to be 382 million individuals, increasing to almost 592 million by 2035 [1]. The economic burden of diabetes is also high, in part due to chronic comorbidities such as cardiovascular and renal disease. US healthcare spending because of diabetes and its complications reached almost $306 billion in 2012 [2]. Of note, the aging population, specifi- cally those over 65, are expected to experience the greatest increase ...
Diabetes e nutrição – Artigo 18
Two-year follow-up study of a group-based diabetes medical nutrition therapy and motivational interviewing intervention among African American women
To assess the 2-year efficacy of a combined medical nutrition therapy and motivational interviewing (MI) pilot study intervention and factors that influenced long-term dietary self-care.
Pilot study participants, African American women with type 2 diabetes, completed a 2-year follow-up study visit, including clinical assessments and completion of a dietary self-care questionnaire and a semi-structured interview. Wilcoxon signed-rank tests ...
