Nutrição e Disbiose – Artigo 3
Dysbiosis contributes to chronic constipation development via regulation of serotonin transporter in the intestine
Chronic constipation is a prevalent functional gastrointestinal disorder accompanied with intestinal dysbiosis. However, causal relationship between dysbiosis and constipation remains poorly understood. Serotonin transporter (SERT) is a transmembrane transport protein which re-uptakes excessive 5-hydroxytryptamine (5-HT) from effective location to terminate its physiological effects and involves in regulating gastrointestinal motility. In this study, fecal microbiota ...
Nutrição e Disbiose – Artigo 2
Dysbiosis caused by vitamin D receptor deficiency confers colonization resistance to Citrobacter rodentium through modulation of innate lymphoid cells
Abstract
Vitamin D receptor (VDR) knockout (KO) mice had fewer Citrobacter rodentium in the feces than wild-type (WT) mice and the kinetics of clearance was faster in VDR KO than WT mice. VDR KO mice had more IL-22 producing innate lymphoid cells (ILC), and more anti-bacterial peptides than WT mice. The increased ILC in the VDR KO mice was a cell autonomous effect of VDR deficiency on ILC frequencies. BM transplantation from VDR KO mice ...
Nutrição e Disbiose – Artigo 1
Bridging the Gap between Gut Microbial Dysbiosis and Cardiovascular Diseases
Abstract: The human gut is heavily colonized by a community of microbiota, primarily bacteria, that exists in a symbiotic relationship with the host and plays a critical role in maintaining host homeostasis. The consumption of a high-fat (HF) diet has been shown to induce gut dysbiosis and reduce intestinal integrity. Recent studies have revealed that dysbiosis contributes to the progression of cardiovascular diseases (CVDs) by promoting two major CVD risk factors—atherosclerosis and hypertension. Imbala...
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Revista Brasileira de Nutrição Funcional – 2018 – edição 74
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A individualidade bioquímica é um pilar fundamental da nutrição funcional, que direciona condutas personalizadas para cada indivíduo. Esta edição traz uma revisão que tem como tema central a aplicação da nutrigenômica na determinação do melhor tipo de dieta, mostrando o impacto das variações genéticas nas nossas necessidades nutricionais individuais.
Contribuindo para a atualização e prática clínica dos nutricionistas em relação às doenças crônicas não transmissíveis, ...
Nutrição e Exposição aos metais tóxicos e efeitos à saúde – Artigo 20
Neurotoxicity from prenatal and postnatal exposure to methylmercury
Abstract
The extent to which postnatal methylmercury exposure contributes to neurobehavioral delays is
uncertain. Confounding may occur because the child's dietary exposure likely correlates with the
mother's. This conundrum was examined in the Faroese birth cohort 1 born in 1986–1987.
Exposure parameters included mercury concentrations in maternal hair at parturition, cord blood,
and child blood and hair at the age-7 clinical examination (N = 923). In regression analyses, the
child's current blood-mercury at age ...
Nutrição e Exposição aos metais tóxicos e efeitos à saúde – Artigo 19
Mercury contamination in Southern New England coastal fisheries and dietary habits of recreational anglers and their families: Implications to human health and issuance of consumption advisories
Abstract
Total mercury (Hg) was measured in coastal fishes from Southern New England (RI, USA), and Hg exposure was estimated for anglers and family members that consumed these resources. Fish Hg was positively related to total length (n = 2028 across 7 fish species), and interspecies differences were evident among legally harvestable fish. Many recreational anglers and their families experienced ...
Nutrição e Exposição aos metais tóxicos e efeitos à saúde – Artigo 18
Low-Level Toxic Metal Exposure in Healthy Weaning-Age Infants: Association with Growth, Dietary Intake, and Iron Deficiency
Abstract: Even low levels of toxic metal exposure (As, Cd, Hg, and Pb) in infancy might be
harmful to children’s development. This study investigated toxic metal exposure on healthy
weaning-age infants and its relationship with growth, diet, and iron/anemia status. The weight,
height, head circumference, whole blood levels of four toxic metals, hemoglobin, and serum ferritin
of healthy infants was measured. Among 210 infants with a median age of 11.4 months ...
