Nutrição e Depressão – Artigo 20
Vitamin D supplementation to prevent depression and poor physical function in
older adults: Study protocol of the D-Vitaal study, a randomized placebo-controlled clinical trial
Abstract
Background: Depressive symptoms and decreased physical functioning are interrelated conditions and common in older persons, causing significant individual and societal burden. Evidence suggests that vitamin D supplementation may be beneficial for both mental and physical functioning. However, previous randomized controlled trials have yielded inconsistent results and often had suboptimal designs. ...
Nutrição e Depressão – Artigo 19
Therapeutic Effects of Phytochemicals and Medicinal Herbs on Depression
Background. Depression is a recurrent, common, and potentially life-threatening psychiatric disease related to multiple assignable causes. Although conventional antidepressant therapy can help relieve symptoms of depression and prevent relapse of the illness, complementary therapies are required due to disadvantage of the current therapy such as adverse effects. Moreover, a number of studies have researched adjunctive therapeutic approaches to improve outcomes for depression patients. Purpose. One potential comp...
Nutrição e Depressão – Artigo 18
The Role of Vitamin D in the Prevention of Late-life Depression
Abstract
BACKGROUND—In this article, we review current evidence regarding potential benefits of vitamin D for improving mood and reducing depression risk in older adults. We summarize gaps in knowledge and describe future efforts that may clarify the role of vitamin D in late-life depression prevention.
METHODS—MEDLINE and PsychINFO databases were searched for all articles on vitamin D and mood that had been published up to and including May 2015. Observational studies and randomized trials with 50 or more participants ...
Nutrição e Depressão – Artigo 17
The Role of Nutrients in Protecting Mitochondrial Function and Neurotransmitter Signaling: Implications for the Treatment of Depression, PTSD, and Suicidal Behaviors
Abstract
Numerous studies have linked severe stress to the development of major depressive disorder (MDD), and suicidal behaviors. Furthermore, recent preclinical studies from our laboratory and others have demonstrated that in rodents, chronic stress and the stress hormone cortisol has caused oxidative damage to mitochondrial function and membrane lipids in the brain. Mitochondria play a key role in synaptic neurotransmitter ...
Nutrição e Depressão – Artigo 16
Prevention of depression through nutritional strategies in high-risk persons:
rationale and design of the MooDFOOD prevention trial
Abstract
Background: Obesity and depression are two prevalent conditions that are costly to individuals and society. The bidirectional association of obesity with depression, in which unhealthy dietary patterns may play an important role, has been well established. Few experimental studies have been conducted to investigate whether supplementing specific nutrients or improving diet and food-related behaviors can prevent depression in overweight person...
Nutrição e Depressão – Artigo 15
Omega-3 Fatty Acids and Depression: Scientific Evidence and Biological Mechanisms
The changing of omega-6/omega-3 polyunsaturated fatty acids (PUFA) in the food supply of Western societies occurred over the last 150 years is thought to promote the pathogenesis ofmany inflammatory-related diseases, including depressive disorders. Several epidemiological studies reported a significant inverse correlation between intake of oily fish and depression or bipolar disorders. Studies conducted specifically on the association between omega-3 intake and depression reported contrasting results, ...
Nutrição e Depressão – Artigo 14
Nutritional Aspects of Depression
Abstract
Several nutrition, food and dietary compounds have been suggested to be involved in the onset and maintenance of depressive disorders and in the severity of depressive symptoms.
Nutritional compounds might modulate depression associated biomarkers and parallel the
development of depression, obesity and diabetes. In this context, recent studies revealed new
mediators of both energy homeostasis and mood changes (i.e. IGF-1, NPY, BDNF, ghrelin, leptin, CCK, GLP-1, AGE, glucose metabolism and microbiota) acting in gut brain circuits. In this ...
Nutrição e Depressão – Artigo 13
Nutrition Depression in the Community-Based Oldest-Old
The number of older adults continues to increase in all healthcare settings. The majority of older adults are living in the community. Most are dealing with at least one chronic physical illness or mental health concern. Nutritional status and depression, key indicators of overall health, have a complex and interdependent relationship. Clinicians must understand factors that affect nutrition and depression to promote positive health outcomes and enhance the overall quality of life for the oldest-old in the community.
