Nutrição e Tireoidite de Hashimoto – Artigo 4
Evaluation of Xerostomia and salivary flow rate in Hashimoto’s Thyroiditis
Abstract
Background: One of the most common causes of hypothyroidism is Hashimoto´s Thyroiditis (HT). Early detection
of dry mouth is critical in preserving and promoting systemic and oral health. In this study we have assessed, for the first time, salivary function and xerostomia in HT patients who have not been involved with Sjögren´s syndrome.
Material and Methods: HT was diagnosed in 40 patients based on clinical findings and positive anti-thyroid peroxidase antibodies (anti-TPO). Controls, matched ...
Nutrição e Tireoidite de Hashimoto – Artigo 3
Association between Hashimoto’s thyroiditis and cholelithiasis: a retrospective cohort study in Taiwan
Abstract
Objective To investigate the relation of Hashimoto’s thyroiditis (HT) to cholelithiasis and cholecystectomy in a
retrospective population-based study. Setting Cohort study. Participants We identified 1268 patients aged ≥20 years
with HT between 2000 and 2010 as the study cohort.
Primary and secondary outcome measures Patients without HT were randomly selected from a database and propensity-matched with the study cohort at a 1:4 ratio according to age, sex, ...
Nutrição e Tireoidite de Hashimoto – Artigo 2
Altered expression of CTLA-4, CD28, VDR, and CD45 mRNA in T cells of patients with Hashimoto’s thyroiditis — a pilot study
Abstract
Introduction: CD28/T-cell receptor (TCR)/cytotoxic T-lymphocyte antigen 4 (CTLA4) complex controls T-cell tolerance and autoimmunity in Hashimoto’s thyroiditis (HT). In addition, CD45 protein tyrosine phosphatase (PTPase) and vitamin D receptor (VDR) cooperatively interact with the TCR complex to affect autoimmune processes central to the pathogenesis of HT. Nevertheless, their role in HT aetiology has been less well established. In this study, we ...
Nutrição e Tireoidite de Hashimoto – Artigo 1
25-Hydroxyvitamin D serum level in Hashimoto’s thyroiditis, but not Graves’ disease is relatively deficient
Abstract. Vitamin D is a modulator of both the innate and adaptive immune system. As vitamin D deficiency was a risk factor for some autoimmune diseases, we aimed to evaluate the serum vitamin D levels in autoimmune thyroid diseases(AITD) including Graves’ disease (GD) and Hashimoto’s thyroiditis (HT) and investigated the association between serumvitamin D levels and AITD. 175 AITD patients including 51 GD, 61 euthyroid HT (mild HT), 63 euthyroid HT patientswith hypothyro...
Nutrição e Doença Celíaca – Artigo 20
The Role of Gluten in Celiac Disease and Type 1 Diabetes
Abstract: Celiac disease (CD) and type 1 diabetes (T1D) are autoimmune conditions in which dietary gluten has been proven or suggested to play a pathogenic role. In CD; gluten is established as the instigator of autoimmunity; the autoimmune process is halted by removing gluten from the diet; which allows for resolution of celiac autoimmune enteropathy and subsequent normalization of serological markers of the disease. However; an analogous causative agent has not yet been identified for T1D. Nevertheless; the role of dietary ...
Nutrição e Doença Celíaca – Artigo 19
The neurologic significance of celiac disease biomarkers
ABSTRACT
Objective: To report neurologic phenotypes and their etiologies determined among 68 patients with either (1) celiac disease (CD) or (2) no CD, but gliadin antibody positivity (2002–2012).
Methods: Neurologic patients included both those with the CD-prerequisite major histocompatibility complex class II human leukocyte antigen (HLA)-DQ2/DQ8 haplotype, and those without. The 3 groups were as follows: group 1 (n 5 44), CD or transglutaminase (Tg)-2/deamidated gliadin immunoglobulin (Ig)A/IgG detected; group 2 (n 5 15), ...
Nutrição e Doença Celíaca – Artigo 18
Screening for celiac disease in poorly controlled type 2 diabetes mellitus: worth it or not?
Abstract
Background: Recent studies have demonstrated that immune factors might have a role in the pathophysiology of
insulin resistance and type 2 diabetes mellitus (T2DM). Inappropriate glycemic control in patients with T2DM is an
important risk factor for the occurrence of diabetes complications. The prevalence of celiac disease (CD) is high in
type 1 diabetes mellitus however, there are scarce data about its prevalence in T2DM. Our aim was to investigate
the prevalence of celiac disease ...
Nutrição e Doença Celíaca – Artigo 17
Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease
Abstract
Viral infections have been proposed to elicit pathological processes leading to the initiation of T helper 1 (TH1) immunity against dietary gluten and celiac disease (CeD). To test this hypothesis and gain insights into mechanisms underlying virus-induced loss of tolerance to dietary antigens, we developed a viral infection model that makes use of two reovirus strains that infect the intestine but differ in their immunopathological outcomes. Reovirus is an avirulent ...
