Nutrição e Diabetes Mellitus I – Artigo 12
Impact of type 1 diabetes mellitus and celiac disease on nutrition and quality of life
OBJECTIVE: Type 1 diabetes mellitus (T1DM) and celiac disease (CD) are autoimmune diseases and have similar genetic patterns. T1DM treatment is based on diet, physical activity and insulin therapy, whereas CD depends on dietary changes with restriction of wheat, rye and barley. The aim of the study was to evaluate the quality of life (QoL) of individuals with the association of T1DM and CD, to characterize their nutritional status and to compare it with those with only one disease and healthier ...
Nutrição e Diabetes Mellitus I – Artigo 11
Immunomodulatory Effect of Vitamin D and Its Potential Role in the Prevention and Treatment of
Type 1 Diabetes Mellitus—A Narrative Review
Abstract: Type 1 diabetes mellitus is a chronic autoimmune disease associated with degeneration of pancreatic β-cells that results in an inability to produce insulin and the need for exogenous insulin administration. It is a significant global health problem as the incidence of this disorder is increasing worldwide. The causes are still poorly understood, although it certainly has genetic and environmental origins. Vitamin D formed profusely in ...
Nutrição e Diabetes Mellitus I – Artigo 10
Gastrointestinal Microbiota and Type 1 Diabetes Mellitus: The State of Art
Abstract: The incidence of autoimmune type 1 diabetes (T1DM) is increasing worldwide and disease onset tends to occur at a younger age. Unfortunately, clinical trials aiming to detect predictive factors of disease, in individuals with a high risk of T1DM, reported negative results. Hence, actually there are no tools or strategies to prevent T1DM onset. The importance of the gut microbiome in autoimmune diseases is increasingly recognized and recent data suggest that intestinal dysbiosis has a pathogenic role ...
Nutrição e Diabetes Mellitus I – Artigo 9
FGF-23/Vitamin D Axis in Type 1 Diabetes: The Potential Role of Mineral Metabolism in
Arterial Stiffness
Abstract
Objective
To investigate the usefulness of Fibroblast Growth Factor 23 (FGF-23) and vitamin D as possible biomarkers of pre-clinical atherosclerosis, assessed as arterial stiffness (AS), in a group of subjects with type 1 diabetes (T1DM) and no previous cardiovascular events.
Research Design and Methods
68 T1DM patients and 68 age- and sex-matched controls were evaluated for 1) age, sex, diabetes duration, physical activity, smoking, alcohol intake, BMI, blood pressu...
Nutrição e Diabetes Mellitus I – Artigo 8
Evaluating a dietary pattern in adolescents with type 1 diabetes mellitus: The dash-d approach
Abstract
Objective: Adolescents with type 1 diabetes (T1DM) must consider multiple factors in diet planning, including glycemic control and cardiovascular disease prevention, while ensuring adequate nutrition for growth. We examined diet composition, quality, and compliance for two dietary patterns - the traditional Dietary Approaches to Stop Hypertension (DASH) and a modified version of DASH in this population. Methods and Findings: Two feeding studies were conducted. First, adolescents ...
Nutrição e Diabetes Mellitus I – Artigo 7
Effect of Vitamins C and E on Endothelial Function in Type 1 Diabetes Mellitus
Background/Objectives. Endothelial dysfunction due to hyperglycemia-induced oxidative damage is an important predictor of future cardiovascular risk in patients with type 1 diabetes mellitus (T1DM) and is present in adolescent T1DM. We hypothesized that combined treatment with the antioxidant vitamins C and E might improve endothelial function (EF) and other biochemical risk factors in adolescents with T1DM. Subjects/Methods. Open-label antioxidant supplementation was given for six weeks with endpoint ...
Nutrição e Diabetes Mellitus I – Artigo 6
Eating Disorders and Disordered Eating Symptoms in Adolescents with Type 1 Diabetes
Abstract: Eating problems in adolescents with type 1 diabetes (T1D) can be divided into two groups. The first includes the diagnosed eating disorders (EDs), i.e., diseases specifically identified by defined signs and symptoms for which a degree of severity has been established, such as anorexia nervosa, bulimia nervosa, binge-eating disorder, pica, and rumination. The second is the group of disordered eating symptoms (DES), which include behaviors such as dieting for weight loss, binge eating, self-...
Nutrição e Diabetes Mellitus I – Artigo 5
Divergent Changes in Plasma AGEs and sRAGE Isoforms Following an Overnight Fast in T1DM
Abstract: Advanced glycation end products (AGEs) promote the development of diabetic complications through activation of their receptor (RAGE). Isoforms of soluble RAGE (sRAGE) sequester AGEs and protect against RAGE-mediated diabetic complications. We investigated the effect of an overnight fast on circulating metabolic substrates, hormones, AGEs, and sRAGE isoforms in 26 individuals with type 1 diabetes (T1DM). Blood was collected from 26 young (18–30 years) T1DM patients on insulin pumps ...
