Nutrição e Obesidade – Artigo 6
Gene-Diet Interaction and Precision Nutrition in Obesity
Abstract: The rapid rise of obesity during the past decades has coincided with a profound shift of our living environment, including unhealthy dietary patterns, a sedentary lifestyle, and physical inactivity. Genetic predisposition to obesity may have interacted with such an obesogenic environment in determining the obesity epidemic. Growing studies have found that changes in adiposity and metabolic response to low-calorie weight loss diets might be modified by genetic variants related to obesity, metabolic status and preference ...
Nutrição e Obesidade – Artigo 5
Dietary capsaicin and its anti-obesity potency: from mechanism to clinical implications
Obesity is a growing public health problem, which has now been considered as a pandemic non-communicable disease. However, the efficacy of several approaches for weight loss is limited and variable. Thus, alternative anti-obesity treatments are urgently warranted, which should be effective, safe, and widely available. Active compounds isolated from herbs are similar with the practice of Traditional Chinese Medicine, which has a holistic approach
that can target to several organs and tissues in the ...
Nutrição e Obesidade – Artigo 4
Diet, Microbiota, Obesity, and NAFLD: A Dangerous Quartet
Abstract: Recently, the importance of the gut-liver-adipose tissue axis has become evident. Nonalcoholic fatty liver disease (NAFLD) is the hepatic disease of a systemic metabolic disorder that radiates from energy-surplus induced adiposopathy. The gut microbiota has tremendous influences in our whole-body metabolism, and is crucial for our well-being and health. Microorganisms precede humans in more than 400 million years and our guest flora evolved with us in order to help us face aggressor microorganisms, to help us ...
Nutrição e Obesidade – Artigo 3
Blaming the brain for obesity: Integration of hedonic and homeostatic mechanisms
Abstract
The brain plays a key role in the controls of energy intake and expenditure and many genes associated with obesity are expressed in the central nervous system. Technological and conceptual advances in both basic and clinical neurosciences have expanded the traditional view of homeostatic regulation of body weight by mainly the hypothalamus to include hedonic controls of appetite by cortical and subcortical brain areas processing external sensory information, reward, cognition, and executive ...
Nutrição e Obesidade – Artigo 2
Bariatric Surgery and Precision Nutrition
Abstract: This review provides a literature overview of new findings relating nutritional genomics and bariatric surgery. It also describes the importance of nutritional genomics concepts in personalized bariatric management. It includes a discussion of the potential role bariatric surgery plays in altering the three pillars of nutritional genomics: nutrigenetics, nutrigenomics, and epigenetics. We present studies that show the effect of each patient’s genetic and epigenetic variables on the response to surgical weight loss treatment. We ...
Nutrição e Obesidade – Artigo 1
An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity
Abstract: In the past three decades, total fat and saturated fat intake as a percentage of total calories has continuously decreased in Western diets, while the intake of omega-6 fatty acid increased and the omega-3 fatty acid decreased, resulting in a large increase in the omega-6/omega-3 ratio from 1:1 during evolution to 20:1 today or even higher. This change in the composition of fatty acids parallels a significant increase in the prevalence of overweight and obesity. Experimental studies have ...
Nutrição e ELA (Esclerose Lateral Amiotrófica) – Artigo 20
Vitamin D in amyotrophic lateral sclerosis
Summary
Vitamin D supplementation has been proposed as a potential treatment to delay amyotrophic lateral sclerosis (ALS) progression. The aims of this study were to compare retrospectively vitamin D blood levels in ALS patients with those in healthy subjects; to correlate vitamin
D blood levels with clinical functions in patients; and to evaluate whether administration of vitamin D could modify the clinical progression of the disease. Vitamin D blood levels were evaluated in 57ALS patients and in 57 healthy subjects. In the ALS patients ...
Nutrição e ELA (Esclerose Lateral Amiotrófica) – Artigo 19
The influence of the initial state of nutrition on the lifespan of patients with
amyotrophic lateral sclerosis (ALS) during home enteral nutrition
La influencia del estado inicial de la nutrición en la esperanza de vida de pacientes con esclerosis lateral amiotrófica (ALS) durante la nutrición enteral en casa
Resumen
Objetivo: la esclerosis lateral amiotrófica (ELA) es una enfermedad crónica, neurodegenerativa que genera malnutrición. El objetivo principal de este estudio es analizar el impacto de la malnutrición en el curso de la enfermedad y la sobrevida a largo plazo.
Mat...
