Nutrição e Osteoporose – Artigo 10
Nutrition and osteoporosis prevention for the orthopaedic surgeon: a wholefoods approach
Introduction
Osteoporosis is a silent but progressive disease affecting the density and quality of bone while greatly increasing
fracture risk.1 Globally, around one in three women and one in five men are at risk of an osteoporotic fracture, with the most common fractures being at the hip, spine or wrist.1 The pathogenesis of osteoporosis is multi-faceted, consisting of intricate interplay between physiological processes, including hormonal status, along with genetic and environmental ...
Nutrição e Osteoporose – Artigo 9
Managing Osteoporosis Patients after Long-Term Bisphosphonate Treatment: Report of a Task Force of the American Society for Bone and Mineral Research
Abstract
Bisphosphonates (BPs) are the most commonly used medications for osteoporosis, but optimal duration of therapy is unknown. This ASBMR report provides guidance on BP therapy duration with a risk benefit perspective.
Two trials provided evidence for long-term BP use. In the Fracture Intervention Trial Long-term Extension (FLEX), postmenopausal women receiving alendronate for 10 years had fewer clinical vertebral fractures than ...
Nutrição e Osteoporose – Artigo 8
Management of Osteoporosis in Chronic Kidney Disease
Abstract:
Chronic kidney disease (CKD) patients with coexisting osteoporosis are becoming common. Many of the therapeutic agents used to treat osteoporosis are known to be affected by the renal function. It is generally
thought that osteoporosis in G1 to G3 CKD patients can be treated as in non-CKD patients with osteoporosis. In stage 4 or more advanced CKD patients and CKD patients on dialysis with osteoporosis, however, bisphosphonates must be used with caution, bearing in mind the potential development of such disorders as ady...
Nutrição e Osteoporose – Artigo 7
International Osteoporosis Foundation and European Calcified Tissue Society Working Group. Recommendations for the screening of adherence to oral bisphosphonates
Abstract
Background—Low adherence to oral bisphosphonates is a common problem that jeopardizes the efficacy of treatment of osteoporosis. No clear screening strategy for the assessment of compliance is widely accepted in these patients.
Methods—The International Osteoporosis Foundation and the European Calcified Tissue Society have convened a working group to propose a screening strategy to detect a lack of adherence ...
Nutrição e Osteoporose – Artigo 6
Effects of whole body vibration exercises on bone mineral density of women with postmenopausal osteoporosis without medications: novel findings and literature review
Abstract
Objectives: The aim of this study was to review the literature about the effect of whole body vibration exercise in the BMD in patients with postmenopausal osteoporosis without medications. Methods: A systematic review was performed.
Results: The frequency of the mechanical vibration used in the protocols has varied from 12 to 90 Hz. The time used in the protocols varied from 2 up to 22 months. Techniques with ...
Nutrição e Osteoporose – Artigo 5
COPD and osteoporosis: links, risks, and treatment challenges
Abstract: Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory airway disease associated with various systemic comorbidities including osteoporosis. Osteoporosis and its related fractures are common and have significant impacts on quality of life and even respiratory function in patients with COPD. COPD-associated osteoporosis is however extremely undertreated. Recent studies have suggested that both decreased bone mineral density (BMD) and impaired bone quality contribute to bone fragility, causing ...
Nutrição e Osteoporose – Artigo 4
Calcium plus vitamin D supplementation and risk of fractures: an updated meta-analysis from the National Osteoporosis Foundation
Abstract
Summary The aim was to meta-analyze randomized controlled trials of calcium plus vitamin D supplementation and fracture prevention. Meta-analysis showed a significant 15 % reduced risk of total fractures (summary relative risk estimate [SRRE], 0.85; 95 % confidence interval [CI], 0.73–0.98) and a 30 % reduced risk of hip fractures (SRRE, 0.70; 95 % CI, 0.56–0.87). Introduction Calcium plus vitamin D supplementation has been widely recomme...
Nutrição e Osteoporose – Artigo 3
Associations between VDR Gene Polymorphisms and Osteoporosis Risk and Bone Mineral Density
in Postmenopausal Women: A systematic review and MetaAnalysis
Results on the relationships between vitamin D receptor (VDR) gene polymorphisms and postmenopausal osteoporosis (PMOP) susceptibility and bone mineral density (BMD) are conficting. The aim of the study is to identify more eligible studies that calculated pooled OR and WMD with 95% CI to assess their associations. Overall, there were signifcant correlations between VDR ApaI, VDR FokI and PMOP susceptibility. Subgroup analysis ...
