month : 04/2020 49 results

Nutrição e Sistema Imune – Artigo 10

Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation Abstract: Glutamine is the most abundant and versatile amino acid in the body. In health and disease, the rate of glutamine consumption by immune cells is similar or greater than glucose. For instance, in vitro and in vivo studies have determined that glutamine is an essential nutrient for lymphocyte proliferation and cytokine production, macrophage phagocytic plus secretory activities, and neutrophil bacterial killing. Glutamine release to the circulation and availability is mainly controlled by key ...

Nutrição e Sistema Imune – Artigo 9

Effects of Vitamin A Supplementation on Immune Responses and Correlation with Clinical Outcomes INTRODUCTION The term vitamin A designates a group of retinoid compounds with the biologic activity of all-trans-retinol. Retinoids usually consist of four isoprenoid units with five conjugated carbon-carbon double bonds (141). Preformed vitamin A can be obtained mostly from dietary animal sources (liver, fish liver oils, eggs, and dairy products) as retinyl palmitate, whereas carotenoids that can be converted into retinol are obtained from vegetable foodstuffs (dark-green leafy ...

Nutrição e Sistema Imune – Artigo 8

RELAÇÃO DO CONSUMO DE VITAMINAS E MINERAIS COM O SISTEMA IMUNITÁRIO: UMA BREVE REVISÃO RESUMO: O sistema imunitário é o sistema de defesa do corpo humano, e é constituído por uma complexa rede de células e moléculas dispersas por todo o organismo. Este sistema tem importante relação com a nutrição pois há interação entre a ingestão adequada de nutrientes, o aumento no estresse oxidativo e a ocorrência de processos infecciosos, com depleção imunitária. Esse artigo trata-se de revisão de literatura colocando em destaque os principais nutrientes que agem em benefício ...

Nutrição e Sistema Imune – Artigo 7

Nutritional Modulation of Immune Function: Analysis of Evidence, Mechanisms, and Clinical Relevance It is well-established that the nutritional deficiency or inadequacy can impair immune functions. Growing evidence suggests that for certain nutrients increased intake above currently recommended levels may help optimize immune functions including improving defense function and thus resistance to infection, while maintaining tolerance. This review will examine the data representing the research on prominent intervention agents n-3 polyunsaturated fatty acids (PUFA), micronutrients ...

Nutrição e Sistema Imune – Artigo 6

Micronutrientes e sistema imunológico Resumo Objetivo: A ingestão inadequada de alguns nutrientes pode estar associada a diferentes prejuízos na capacidade normal de defesa celular e/ou humoral, bem como na predisposição de doenças alérgicas. A presença de radicais livres parece ter papel relevante no desenvolvimento de doenças relacionadas ao sistema imunológico. Tendo em vista a elevada prevalência das deficiências de ferro, zinco e vitamina A em nosso meio, o objetivo dessa revisão foi abordar a relação entre a deficiência desses micronutrientes e o sistema ...

Nutrição e Sistema Imune – Artigo 5

A Review of Micronutrients and the Immune System–Working in Harmony to Reduce the Risk of Infection Abstract: Immune support by micronutrients is historically based on vitamin C deficiency and supplementation in scurvy in early times. It has since been established that the complex, integrated immune system needs multiple specific micronutrients, including vitamins A, D, C, E, B6, and B12, folate, zinc, iron, copper, and selenium, which play vital, often synergistic roles at every stage of the immune response. Adequate amounts are essential to ensure the proper function of physical ...

Nutrição e Sistema Imune – Artigo 4

Immune Function and Micronutrient Requirements Change over the Life Course Abstract: As humans age, the risk and severity of infections vary in line with immune competence according to how the immune system develops, matures, and declines. Several factors influence the immune system and its competence, including nutrition. A bidirectional relationship among nutrition, infection and immunity exists: changes in one component affect the others. For example, distinct immune features present during each life stage may affect the type, prevalence, and severity of infections, while poor ...

Nutrição e Sistema Imune – Artigo 3

Zinc Signals and Immunity Abstract: Zinc homeostasis is crucial for an adequate function of the immune system. Zinc deficiency as well as zinc excess result in severe disturbances in immune cell numbers and activities, which can result in increased susceptibility to infections and development of especially inflammatory diseases. This review focuses on the role of zinc in regulating intracellular signaling pathways in innate as well as adaptive immune cells. Main underlying molecular mechanisms and targets affected by altered zinc homeostasis, including kinases, caspases, phosphatases, ...