Nutrição e Esteatose – Artigo 8
Nonalcoholic fatty liver disease (NAFLD) prevention: role of Mediterranean diet and physical activity
Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease in Western countries leading to high morbidity and mortality and is strongly related to obesity (1). Indeed, metabolic syndrome and insulin resistance play a role in the pathogenesis of NAFLD, which involves intrahepatic triglyceride accumulation and inflammation (2). NAFLD is a consequence of genetic predisposition interacting with environmental and behavioral factors. Data within the ...
Nutrição e Esteatose – Artigo 7
Dietary approach in the treatment of nonalcoholic fatty liver disease
AbstractNonalcoholic fatty liver disease (NAFLD) has been identified as one of the most prevalent chronic liver disease in adults and children populations. NAFLD is usually associated with the metabolic syndrome (MS), which is chiefly related to insulin resistance and its consequences. Insulin resistance has a crucial role in the pathogenesis of hepatic steatosis and potentiallynonalcoholic steatohepatitis (NASH). Because of the contemporary epidemics of MS and obesity, the burden of NAFLD is also expected to rise. ...
Nutrição e Esteatose – Artigo 6
Mediterranean diet and nonalcoholic fatty liver disease
AbstractNonalcoholic fatty liver disease (NAFLD) is emerging as the most common chronic liver disease, and is characterized by a wide spectrum of fat-liver disorders that can result in severe liver disease and cirrhosis. Inflammation and oxidative stress are the major risk factors involved in the pathogenesis of NAFLD. Currently, there is no consensus concerning the pharmacological treatment of NAFLD. However, lifestyle interventions based on exercise and a balanced diet for quality and quantity, are considered the cornerstoneof ...
Nutrição e Esteatose – Artigo 5
Nutritional Intake and the Risk for Non-Alcoholic Fatty Liver Disease (NAFLD)
The prevalence of non-alcoholic fatty liver disease (NAFLD) is rising worldwide, and it is estimated that approximately one billion individuals may be afflicted with NAFLD globally [1,2]. This epidemic has created a large demand for therapeutic interventions in order to treat patients at riskfor the development of end-stage liver disease. As NAFLD is a slowly progressive disease along a spectrum that covers (i) hepatic steatosis defined as non-alcoholic fatty liver (NAFL), (ii) inflammatory non-alcoholic ...
Nutrição e Esteatose – Artigo 4
Role of Nutrition in the Pathogenesis and Prevention of Non-alcoholic Fatty Liver Disease: Recent Updates
AbstractNon-alcoholic fatty liver disease (NAFLD) is an acquired metabolic disease characterized by triglycerides (TGs) deposition in liver induced by other factors rather than alcohol consumption. NAFLD significantly contributes to liver diseases in children and adults. NAFLD pathogenesis is associated with age, gender, race and ethnicity. Insulin resistance, hyperinsulinemia, elevated plasma free fatty acids (FFAs), fatty liver, hepatocyte injury, liver inflammation, oxidative ...
Nutrição e Esteatose – Artigo 3
Relationship between Diet and Non-alcoholic Fatty LiverDisease: A Review Article
AbstractBackground: Diet plays a key role in the development of non-alcoholic fatty liver disease (NAFLD). The aim of this study was to review systematically observational studies available regarding the relationship between food intakes and NAFLD.Methods: We searched Scopus, PubMed, and Cochrane Library databases to identify English observational stu-dies on food groups, dietary patterns, and NAFLD. Cross-sectional, case-control and cohort studies were se-lected and then duplication, topic, type of study, ...
Nutrição e Esteatose – Artigo 2
Impact of Nutritional Changes on Nonalcoholic Fatty Liver Disease
Abstract: Non-alcoholic fatty liver disease (NAFLD) is a major global health threat due to its growing incidence and prevalence. It is becoming the leading cause of liver disease in addition to its strong association with cardio-metabolic disease. Therefore, its prevention and treatment are of strong public interest. Therapeutic approaches emphasize lifestyle modifications including physical activity and the adoption of healthy eating habits that intend to mainly control body weight and cardio-metabolic risk factors ...
Nutrição e Esteatose – Artigo 1
BENEFITS OF LIFESTYLE MODIFICATION IN NAFLD
Compared with our ancestors, Western societies today lead a lifestyle that is much more sedentary, probably as a result of cultural changes stemming from modern socio-economic morays. Taking into account differences in body size, our energy expenditure per kilogram of body weight has been estimated to be ,40% of that of our prehistoric ancestors.1 Current estimatessuggest that 7 out of 10 adults are inactive or lack adequate conditioning,2 and this lack of adequate exercise, combined with dietary indiscretion, has contributed to the worldwide ...
