Nutrição e Fibrose Cística – Intervenção Nutricional
Associados, juntamente com os artigos do mês, vocês receberão uma cartilha resumo com as principais intervenções nutricionais da condição/ doença que é tema do mês! A cartilha resumo poderá ser utilizada como um material de apoio para o momento do atendimento nutricional, facilitando a prescrição de condutas com base nos dados mais recentes dos estudos científicos.
Nutrição e Fibrose Cística – Artigo 19
Improved residual fat malabsorption and growth in children with cystic fibrosis treated with a novel oral structured lipid supplement: A randomized controlled trial
Abstract
Background
In the primary analysis of a 12-month double-blind randomized active placebo-controlled trial, treatment of children with cystic fibrosis (CF) and pancreatic insufficiency (PI) with a readily absorbable structured lipid (Encala™, Envara Health, Wayne, PA) was safe, well-tolerated and improved dietary fat absorption (stool coefficient of fat absorption [CFA]), growth, and plasma fatty acids (FA).
...
Nutrição e Fibrose Cística – Artigo 18
Glutamine Supplementation in Cystic Fibrosis: A Randomized Placebo-Controlled Trial
Summary. Rationale: Pulmonary infection and malnutrition in cystic fibrosis are associated with decreased survival. Glutamine has a possible anti-microbial effect, with a specific impact against Pseudomonas aeruginosa. We aimed to test the hypothesis that oral glutamine supplementation (21 g/day) for 8 weeks in adults with cystic fibrosis would decrease pulmonary inflammation and improve clinical status.
Methods: The study design was a randomized double-blind placebocontrolled study design with an iso-ni...
Nutrição e Fibrose Cística – Artigo 17
ORIGINAL RESEARCH ARTICLES
INTRODUCTION Despite the availability of consensus guidelines for the treatment of vitamin D deficiency,
prospective trials are lacking to examine alternative dosing strategies for adult patients with cystic fibrosis (CF) who do not meet therapeutic goals with standard regimens.
OBJECTIVES The primary objective of this study was to determine the efficacy of high-dose cholecalciferol
supplementation in increasing serum vitamin D (25-OHD) levels in adult patients with CF.
METHODS Patients were eligible for inclusion if they were 18 years or older, had baseline ...
Nutrição e Fibrose Cística – Artigo 16
Vitamin E supplementation in people with cystic fibrosis (Review)
A B S T R A C T
Background
People with cystic fibrosis are at an increased risk of fat-soluble vitamin deficiency, including vitamin E. Vitamin E deficiency can cause a host of conditions such as haemolytic anaemia, cerebellar ataxia and cognitive diBiculties. Vitamin E supplementation is widely recommended for people with cystic fibrosis and aims to ameliorate this deficiency. This is an updated version of the review.
Objectives
To determine the eBects of any level of vitamin E supplementation on the frequency of ...
Nutrição e Fibrose Cística – Artigo 15
Vitamin K supplementation for cystic fibrosis (Review)
A B S T R A C T
Background
Malabsorption and deficiency of fat-soluble vitamins K may occur in cystic fibrosis, a genetic disorder aIecting multiple organs. Vitamin K is known to play an important role in both blood coagulation and bone formation, hence the role of supplementation of vitamin K in this category needs to be reviewed. This is an updated version of the review.
Objectives
To assess the eIects of vitamin K supplementation in people with cystic fibrosis and to investigate the hypotheses that vitamin K will decrease ...
Nutrição e Fibrose Cística – Artigo 14
Vitamin A supplementation for cystic fibrosis (Review)
A B S T R A C T
Background
People with cystic fibrosis and pancreatic insuIiciency are at risk of fat soluble vitamin deficiency as these vitamins (A, D, E and K) are co-absorbed with fat. Thus, some cystic fibrosis centres routinely administer these vitamins as supplements but the centres vary in their approach of addressing the possible development of deficiencies in these vitamins. Vitamin A deficiency causes predominantly eye and skin problems while supplementation of vitamin A to excessive levels may cause harm to the respirat...
Nutrição e Fibrose Cística – Artigo 13
Antioxidant supplementation for lung disease in cystic fibrosis (Review)
A B S T R A C T
Background
Airway infection leads to progressive damage of the lungs in cystic fibrosis (CF) and oxidative stress has been implicated in the etiology. Supplementation of antioxidant micronutrients (vitamin E, vitamin C, beta-carotene and selenium) or N-acetylcysteine (NAC) as a source of glutathione, may therefore potentially help maintain an oxidant-antioxidant balance. Glutathione or NAC can also be inhaled and if administered in this way can also have a mucolytic eHect besides the antioxidant ...
