Nutrição e Enxaqueca – Artigo 18
The Use of Antioxidants in the Treatment of Migraine
Abstract: Despite numerous studies concerning the pathophysiology of migraine, the exact molecular mechanism of disturbances underlying migraine is still unknown. Furthermore, oxidative stress is considered to play a significant role in migraine pathogenesis. The notion of oxidative stress in migraine patients has been discussed for several decades. Over the past few years, among the substances that could potentially be used for migraine treatment, particular attention has been paid to the so-called nutraceutics, including antioxidants. ...
Nutrição e Enxaqueca – Artigo 17
Coenzyme Q10 supplementation for prophylaxis in adult patients with migraine—a meta-analysis
ABSTRACT
Objective: To determine the effects of coenzyme Q10 (CoQ10) for reduction in the severity, frequency of migraine
attacks and duration of headache in adult patients with migraine. Design Systematic review and meta-analysis.
Data sources Cochrane Central Register of Controlled Trials, CENTRAL, MEDLINE, EMBASE, Cumulative Index
to Nursing and Allied Health Literature (CINAHL) and Psychological Information Database (PsycINFO) from
inception till December 2019. Study selection All ...
Nutrição e Enxaqueca – Artigo 16
Therapeutic Implications of Altered Energy Metabolism in Migraine: A State-of-the-Art
Review
Abstract
Currently, the management strategies aimed at the resolution of migraine are pharmacological. Most of these therapies are known to alter the serotonin balance of the brain. Furthermore, therapies blocking the calcitonin gene-related peptide (CGRP) have also proven to be quite effective in their treatments. However, apart from being expensive, these therapies do not influence premonitory and aura symptoms. This suggests an incomplete approach and an inadequate understanding of the ...
Nutrição e Enxaqueca – Artigo 15
A combination of coenzyme Q10, feverfew and magnesium for migraine prophylaxis: a
prospective observational study
Abstract
Background: Feverfew (Tanacetum parthenium L.), magnesium and coenzyme Q10 are frequently used for migraine
prophylaxis. Supplementation with a fixed combination of these three agents (Antemig®, PiLeJe) was investigated in an observational study.
Methods: Adult patients suffering from migraine according to the criteria of the International Headache Society
were enrolled by general practitioners (≥2 migraine attacks during previous month; exclusion of chronic ...
Nutrição e Enxaqueca – Artigo 14
The Role of Magnesium in Neurological Disorders
Abstract: Magnesium is well known for its diverse actions within the human body. From a neurological standpoint, magnesium plays an essential role in nerve transmission and neuromuscular conduction. It also functions in a protective role against excessive excitation that can lead to neuronal cell death (excitotoxicity), and has been implicated in multiple neurological disorders. Due to these important functions within the nervous system, magnesium is a mineral of intense interest for the potential prevention and treatment of neurological ...
Nutrição e Enxaqueca – Artigo 13
Improvement of migraine symptoms with a proprietary supplement containing riboflavin,
magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Abstract
Background: Non-medical, non-pharmacological and pharmacological treatments are recommended for the
prevention of migraine. The purpose of this randomized double-blind placebo controlled, multicenter trial was
to evaluate the efficacy of a proprietary nutritional supplement containing a fixed combination of magnesium,
riboflavin and Q10 as prophylactic treatment for migraine.
Methods: 130 adult migraineurs ...
Nutrição e Enxaqueca – Artigo 12
MAGraine: Magnesium compared to conventional therapy for treatment
of migraines
Abstract
Due to the healthcare burden associated with migraines, prompt and effective treatment is vital to improve patient outcomes and ED workflow. This was a prospective, randomized, double-blind trial. Adults who presented to the ED with a diagnosis of migraine from August of 2019 to March of 2020 were included. Pregnant patients, or with renal impairment were excluded. Patients were randomized to receive intravenous magnesium, prochlorperazine, or metoclopramide. The primary outcome was change in pain ...
Nutrição e Enxaqueca – Artigo 11
Headaches and Magnesium: Mechanisms, Bioavailability, Therapeutic Ecacy and Potential
Advantage of Magnesium Pidolate
Abstract: Magnesium deficiency may occur for several reasons, such as inadequate intake or increased gastrointestinal or renal loss. A large body of literature suggests a relationship between magnesium deficiency and mild and moderate tension-type headaches and migraines. A number of double-blind randomized placebo-controlled trials have shown that magnesium is effcacious in relieving headaches and have led to the recommendation of oral magnesium for headache relief in ...
