Discussão Científica – Dieta Low Fodmap no SII – Profª Silvia Ferolla – Artigo 21
The Relationship between Low Serum Vitamin D Levels and Altered Intestinal Barrier Function in Patients with IBS Diarrhoea Undergoing a Long-Term Low-FODMAP Diet: Novel Observations from a Clinical Trial
Abstract: Decreased serum vitamin D (VD) levels have been associated with gastrointestinal (GI) disorders, including irritable bowel syndrome (IBS). VD can also modulate the intestinal barrier. Given the link between the GI barrier’s alterations and diet, attention has aroused the positive effects of the Low FODMAP Diet (LFD) on IBS patients’ symptom profile. We evaluated the GI ...
Discussão Científica – Dieta Low Fodmap no SII – Profª Silvia Ferolla – Artigo 20
REVIEW ARTICLE
Re-challenging FODMAPs: the low FODMAP diet phase two
Abstract
The low fermentable, oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) diet has good evidence for use in the treatment of patients with irritable bowel syndrome. Importantly, patients are encouraged not to remain on a strict low FODMAP diet long-term, and many patients maintain symptom improvement with a relaxed, moderate FODMAP restriction. The re-challenge phase is crucial to assist patients in identifying speci!c dietary triggers, reduce the level of dietary restriction required, and ...
Discussão Científica – Dieta Low Fodmap no SII – Profª Silvia Ferolla – Artigo 19
Small Intestinal Bacterial Overgrowth—Pathophysiology and Its Implications for Definition and Management
Abstract
The concept of small intestinal bacterial overgrowth (SIBO) arose in the context of maldigestion and malabsorption
among patients with obvious risk factors that permitted the small bowel to be colonized by potentially injurious
colonic microbiota. Such colonization resulted in clinical signs, symptoms, and laboratory abnormalities that were
explicable within a coherent pathophysiological framework. Coincident with advances in medical science, diagnostic
testing evolved ...
Discussão Científica – Dieta Low Fodmap no SII – Profª Silvia Ferolla – Artigo 18
Neurotransmitter and Intestinal Interactions: Focus on the Microbiota-Gut-Brain Axis in Irritable Bowel Syndrome
Abstract
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder of unknown etiology. IBS is caused by a disruption in the gut-brain axis. Given the importance of the gut microbiota in maintaining local and systemic homeostasis of immunity, endocrine, and other physiological processes, the microbiota-gut-brain axis has been proposed as a key regulator in IBS. Neurotransmitters have been shown to affect blood !ow regulation, intestinal motility, nutrient ...
Discussão Científica – Dieta Low Fodmap no SII – Profª Silvia Ferolla – Artigo 17
Optimizing educational methods for the low FODMAP diet in disorders of gut–brain interaction: A feasibility randomized controlled trial
Abstract
Background: A diet low in fermentable oligo-saccharides, di-saccharides, mono-saccharides and polyols (low FODMAP diet) is complex and clinical effectiveness is achieved with dietitian-led education, although dietitian availability in clinical practice varies. This study aimed to assess the feasibility of undertaking a trial to investigate
the clinical and cost-effectiveness of different education delivery methods of the low FODMAP diet in ...
Discussão Científica – Dieta Low Fodmap no SII – Profª Silvia Ferolla – Artigo 16
Low FODMAP Diet: Evidence, Doubts, and Hopes
Abstract: Food is often considered to be a precipitating factor of irritable bowel syndrome (IBS) symptoms. In recent years, there has been a growing interest in FODMAPs (Fermentable Oligo-, Di-, Mono-saccharides, And Polyols), which can be found in many common foods. A low FODMAP diet (LFD) is increasingly suggested for IBS treatment. However, long-term, large, randomized controlled studies are still lacking, and certainties and doubts regarding LFDs have grown, often in a disorderly and confused manner. Some potential LFD limitations and ...
Discussão Científica – Dieta Low Fodmap no SII – Profª Silvia Ferolla – Artigo 15
Low FODMAP Diet: Evidence, Doubts, and Hopes
Abstract: Food is often considered to be a precipitating factor of irritable bowel syndrome (IBS) symptoms. In recent years, there has been a growing interest in FODMAPs (Fermentable Oligo-, Di-, Mono-saccharides, And Polyols), which can be found in many common foods. A low FODMAP diet (LFD) is increasingly suggested for IBS treatment. However, long-term, large, randomized controlled studies are still lacking, and certainties and doubts regarding LFDs have grown, often in a disorderly and confused manner. Some potential LFD limitations and ...
Discussão Científica – Dieta Low Fodmap no SII – Profª Silvia Ferolla – Artigo 14
Increasing Evidence That Irritable Bowel Syndrome and Functional Gastrointestinal Disorders Have a Microbial Pathogenesis
Abstract
The human gastrointestinal tract harbors most of the microbial cells inhabiting the body, collectively known as the microbiota. These microbes have several implications for the maintenance of structural integrity of the gastrointestinal mucosal barrier, immunomodulation, metabolism of nutrients, and protection against pathogens.
Dysfunctions in these mechanisms are linked to a range of conditions in the gastrointestinal tract, including functional gastroint...
