Nutrição e Distrofia Muscular de Duchenne – Artigo 6
Nutritional Issues among Children with Duchenne Muscular Dystrophy—Incidence of Deficiency and Excess Body Mass
Abstract: The progression of Duchenne muscular dystrophy (DMD)requires the assessment of nutritional disturbances at each stage of the disease. The purpose of this study was to assess the nutritional status in various ages of boys with DMD using screening and in-depth evaluation methods. Body composition by Dual X-ray Absorptiometry (DXA), basal metabolic rate (BMR) by indirect calorimetry, a questionnaire of nutritional status—Pediatric Nutrition Screening Tool (PNST)—and ...
Nutrição e Distrofia Muscular de Duchenne – Artigo 5
Duchenne muscular dystrophy
Abstract
Duchenne muscular dystrophy is a severe, progressive, muscle-wasting disease that leads to difficulties with movement and, eventually, to the need for assisted ventilation and premature death. The disease is caused by mutations in DMD (encoding dystrophin) that abolish the production of dystrophin in muscle. Muscles without dystrophin are more sensitive to damage, resulting in progressive loss of muscle tissue and function, in addition to
cardiomyopathy. Recent studies have greatly deepened our understanding of the primary and secondary pathogenetic ...
Nutrição e Distrofia Muscular de Duchenne – Artigo 4
Distrofia muscular de Duchenne: uma revisão narrativa
RESUMO
A Distrofia Muscular de Duchenne (DMD) é uma condição genética progressiva e heterogênea, caracterizada primordialmente pela degradação da força muscular, resultando em incapacidade de locomoção e, eventualmente, comprometimento dos músculos respiratórios e cardíacos. Conhecida pela sua ligação ao cromossomo X, afeta majoritariamente indivíduos do sexo masculino e mulheres com Síndrome de Turner, devido à sua transmissão recessiva ligada ao X. Este estudo tem como objetivo principal definir a Distrofia ...
Nutrição e Distrofia Muscular de Duchenne – Artigo 3
Recomendações nutricionais na Distrofia Muscular de Duchenne
RESUMO
OBJETIVO: Pesquisar as recomendações nutricionais para pacientes com Distrofia Muscular de Duchenne (DMD).
MÉTODO: Trata- se de uma revisão integrativa da literatura, através de levantamento bibliográfico nas bases cientificas PubMed e Scielo, foram utilizadas as palavras chaves: Distrofia Muscular de Duchenne em combinação com os termos Nutrição, Nutrientes, Nutracêuticos, Vitaminas e Antioxidantes. Foi realizada a busca dos artigos publicados nos últimos 10 anos.
RESULTADOS: Foram selecionados 102 ...
Nutrição e Distrofia Muscular de Duchenne – Artigo 2
Nutrition Strategies to Improve Physical Capabilities in Duchenne Muscular Dystrophy
Duchenne muscular dystrophy (DMD) is a lethal, X-linked recessive, muscle-wasting disease1 caused by mutations in the dystrophin gene, located on chromosome Xp21. Mutations of the dystrophin gene result in the absence of the dystrophin protein, which leads to an impaired linkage between the F-actin cytoskeleton and the extracellular matrix protein laminin 2 via the membrane-bound dystrophin-glycoprotein complex (DGC).2,3 In the absence of dystrophin, the mechanical links from the cytoskeleton of the muscle ...
Nutrição e Distrofia Muscular de Duchenne – Artigo 1
Nutritional Challenges in Duchenne Muscular Dystrophy
Abstract: Neuromuscular diseases (NMDs) represent a heterogeneous group of acquired or inherited conditions. Nutritional complications are frequent in NMDs, but they are sometimes underestimated. With the prolongation of survival in patients with NMDs, there are several nutritional aspects that are important to consider, including the deleterious effects of overnutrition on glucose metabolism, mobility, and respiratory and cardiologic functions; the impact of hyponutrition on muscle and ventilatory function; constipation and other ...
