Nutrição e Síndrome de Cushing – Artigo 4
Glucocorticoid Regulation of Food-Choice Behaviorin Humans: Evidence from Cushing’s Syndrome
The mechanisms by which glucocorticoids regulate food intake and resulting body mass in human sare not well-understood. One potential mechanism could involve modulation of reward processing, but human stress models examining effects of glucocorticoids on behavior contain important confounds. Here, we studied individuals with Cushing’s syndrome, a rare endocrine disorder characterized by chronic excess endogenous glucocorticoids. Twenty-three patients with Cushing’s syndrome (13 with active ...
Nutrição e Síndrome de Cushing – Artigo 3
Very Low-Calorie Ketogenic Diet: A Potential Application in the Treatment of Hypercortisolism Comorbidities
Abstract: A very low-calorie ketogenic diet (VLCKD) is characterized by low daily caloric intake (less than 800 kcal/day), low carbohydrate intake (<50 g/day) and normoproteic (1–1.5 g of protein/kg of ideal body weight) contents. It induces a significant weight loss and an improvement in lipid parameters, blood pressure, glycaemic indices and insulin sensitivity in patients with obesity and type 2 diabetes mellitus. Cushing’s syndrome (CS) is characterized by an endogenous or ...
Nutrição e Síndrome de Cushing – Artigo 2
A prospective study of appetite and food craving in 30 patients with Cushing’s disease
Abstract
Context—Glucocorticoid (GC) exposure increases food intake, but the mechanisms in humans are not known. Investigation of appetite and food craving has not been done in patients with chronic GC exposure due to Cushing’s disease (CD), either before or after treatment, and could provide insight into mechanisms of food intake and obesity in these patients.
Purpose—To examine whether surgical remission of CD changes appetite (prospective consumption, hunger, satisfaction, and fullness) and ...
Nutrição e Síndrome de Cushing – Artigo 1
Nutritional Intervention in Cushing’s Disease: The Ketogenic Diet’s Effects on Metabolic Comorbidities and Adrenal Steroids
Abstract:
Background: a very low-calorie ketogenic diet (VLCKD) is associated with improvement of metabolic and cardiovascular disorders. We aimed to evaluate the effects of a VLCKD in patients with Cushing’s disease (CD) as adjunctive therapy to treatment for the primary disease.
Methods: we evaluated clinical, hormonal and metabolic parameters in 15 patients with CD and 15 controls at baseline after 1 week and 3 weeks of VLCKD and, further, after 2 weeks of ...
Nutrição e Doenças da Paratireoide – Intervenção Nutricional
Associados, juntamente com os artigos do mês, vocês receberão uma cartilha resumo com as principais intervenções nutricionais da condição/ doença que é tema do mês! A cartilha resumo poderá ser utilizada como um material de apoio para o momento do atendimento nutricional, facilitando a prescrição de condutas com base nos dados mais recentes dos estudos científicos.
Nutrição e Doenças da Paratireoide – Artigo 10
Hiperparatireoidismo secundário devido à doença renal crônica e acesso ao tratamento clínico e à paratireoidectomia no Brasil: uma pesquisa nacional
Resumo
Introdução: A doença renal crônica (DRC) pode levar ao hiperparatireoidismo secundário (HPTS) e seu tratamento baseia-se no controle da hiperfosfatemia, hipocalcemia e níveis séricos de paratormônio (PTH). Apesar dos avanços no tratamento do HPTS, a falha terapêutica é frequente, e pacientes com DRC em diálise demandam paratireoidectomia (PTx).
Objetivo: Atualizar a pesquisa de 2011, estimar a prevalência atual de ...
Nutrição e Doenças da Paratireoide – Artigo 9
Normocalcemic primary hyperparathyroidism
Summary
Primary hyperparathyroidism is a common disorder of mineral metabolism characterized by incompletely regulated, excessive secretion of parathyroid hormone from one or more of the parathyroid glands. The historical view of this disease describes two distinct entities marked by two eras. When primary hyperparathyroidism was first discovered about 80 years ago, it was always symptomatic with kidney stones, bone disease and marked hypercalcemia. With the advent of the multichannel autoanalyzer about 40 years ago, the clinical phenotype changed ...
Nutrição e Doenças da Paratireoide – Artigo 8
Tratamento do Hiperparatiroidismo secundário (HPTS)
Pacientes com DRC E3-5
1. Os níveis ideais de PTH não estão estabelecidos para pacientes com DRC E3-5 (Evidência).
1.1 Se os níveis séricos de PTH estiverem em elevação progressiva ou persistentemente acima do valor de referência para o método, deve-se avaliar os níveis séricos de cálcio (Ca), fósforo (P), fração de excreção urinária de P (se disponível), fosfatase alcalina (FA) e 25-hidroxivitamina D (25-vit D) (Evidência).
1.2 As alterações encontradas devem ser corrigidas: sais de Ca para hipocalcemia, ...
