Urinary tract infections in adult general practice patients
SUMMARY
Urinary tract infections (UTIs) are symptomatic infections of the urinary tract, mainly caused by the bacterium Escherichia coli. One in two women suffers from a UTI at least once in her life. The young and sexually active are particularly affected, but it is also seen in elderly, postmenopausal women. The likelihood of recurrence is high. Diagnosis is made with regard to ...
Recent advances in recurrent urinary tract infection from pathogenesis and biomarkers to prevention
Abstract
Recurrent urinary tract infection (UTI) might be one of the most common problems in urological clinics. Recent research has revealed novel evidence about recurrent UTI and it should be considered a different disease from the first infection. The pathogenesis of recurrent UTI might include two mechanisms, bacterial factors and defici...
Urinary Tract Infection: Pathogenesis and Outlook
Abstract
The clinical syndromes comprising urinary tract infection (UTI) continue to exert significant impact on millions of patients worldwide, most of whom are otherwise healthy women. Antibiotic therapy for acute cystitis does not prevent recurrences, which plague up to one fourth of women after an initial UTI. Rising antimicrobial resistance among uropathogenic bacteria further complica...
CMEArticleUrinary tract infections in adults
Yvonne, a successful 26-year-old executive, went to your clinic for dysuria, urinary frequency and urinary urgency of two days’ duration. She had just returned from her honeymoon in Spain. She had no chronic diseases or prior surgical history and was not recently on antibiotics. This was the first time she experienced such symptoms. You performed urine dipstick analysis for her and confirmed the ...
Urinary tract infections: epidemiology, mechanisms of infection and treatment options
Abstract
Urinary tract infections (UTIs) are a severe public health problem and are caused by a range of pathogens, but most commonly by Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Enterococcus faecalis and Staphylococcus saprophyticus. High recurrence rates and increasing antimicrobial resistance among uropathogens threaten to greatly ...
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Zinc in Multiple Sclerosis: A Systematic Review and Meta-Analysis
Abstract
In the last 35 years, zinc (Zn) has been examined for its potential role in the disease multiple sclerosis (MS). This review gives an overview of the possible role of Zn in the pathogenesis of MS as well as a meta-analysis of studies having measured Zn in serum or plasma in patients with MS. Searching the databases PubMed and EMBASE as well as going through reference ...
Vitamin D and Multiple Sclerosis: A Comprehensive Review
ABSTRACT
Numerous observational studies have suggested that there is a correlation between the level of serum vitamin D and MS risk and disease activity. To explore this hypothesis, a literature search of large, prospective, observation studies,
epidemiological studies, and studies using new approaches such as Mendelian randomization was conducted. Available data and ongoing research ...