Nutrição e Epilepsia – Artigo 16

The roles of vitamin B12 and vitamin D in children with intractable epilepsy Abstract: Epilepsy is a chronic neurological disorder. Antiepileptic drugs (AEDs) can cause vitamin B12 or D deficiency in children with intractable epilepsy. In this study, we measured salivary superoxide dismutase (SOD) and metalloproteinsases (MMP) levels in the patients with vitamin B12 and vitamin D treatment. Cytokines and chemokines were measured using ELISA. ...

Nutrição e Epilepsia – Artigo 15

The role of glial cells in epilepsy   BACKGROUND Brain research in the last century was mainly directed at neurons, with the role of glia assumed to be limited to repair, supplying nutrients and above all simply filling the space between neurons. In recent years, the importance of glial cells for normal brain function has been recognised. This article summarises knowledge of glial cells relevant to epilepsy. METHOD The article is based ...

Nutrição e Epilepsia – Artigo 14

The Ketogenic and Atkins Diets Effect on Intractable Epilepsy: A Comparison Abstract Objective Intractable epilepsy is a major difficulty in child neurology, because the numbers of drugs that are available for treatment are limited and new treatments such as diets must be tried. Now there are some diets available for treating patients with intractable epilepsy. The oldest diet is the classic ketogenic diet and one of the newest diets ...

Nutrição e Epilepsia – Artigo 13

Risk factors of vitamin D deficiency in children with epilepsy taking anticonvulsants at initial and during follow-up Purpose: Vitamin D status was evaluated in children with epilepsy taking anticonvulsants to determine the prevalence and risk factors of vitamin D deficiency. Methods: This study was designed as both a cross-sectional and a retrospective cohort study. A sum of 198 children who were diagnosed with epilepsy at the Depart...

Nutrição e Epilepsia – Artigo 12

Neurobiochemical mechanisms of a ketogenic diet in refractory epilepsy Abstract A ketogenic diet is an important therapy used in the control of drug-refractory seizures. Many studies have shown that children and adolescents following ketogenic diets exhibit an over 50% reduction in seizure frequency, which is considered to be clinically relevant. These benefits are based on a diet containing high fat (approximately 90% fat) for 24 ...

Nutrição e Epilepsia – Artigo 11

Low Vitamin D Levels Are Common in Patients with Epilepsy SUMMARY Purpose—Vitamin D is important for bone health, and vitamin D deficiency may contribute to other disorders (e.g., autoimmune, infections, cancer, degenerative, diabetic, and vascular). Enzyme-inducing antiepileptic drugs have been particularly implicated for osteoporosis risk given their effects on vitamin D. We examined the prevalence of vitamin D deficiency in adult ...

Nutrição e Epilepsia – Artigo 10

Long-term impact of the ketogenic diet on growth and resting energy expenditure in children with intractable epilepsy Abstract AIM—The long-term effects of the ketogenic diet, a high fat diet for treating intractable epilepsy, on resting energy expenditure (REE) are unknown. The aim of this study was to evaluate the impact of 15 months of ketogenic diet treatment on growth and REE in children with intractable epilepsy. METHOD—Grow...

Nutrição e Epilepsia – Artigo 9

Ketogenic diet in children with intractable epilepsy: what about resting energy expenditure and growth? The study by Groleau et al.1 looks at the effect of ketogenic diet treatment on resting energy expenditure (REE) and growth in children with intractable epilepsy with and without cerebral palsy (CP) over 15 months. It is an attempt to better understand the metabolic and nutritional long-term effects of the ketogenic diet in children ...