Capsaicin Supplementation Reduces Physical Fatigue and Improves Exercise Performance in Mice
Abstract: Chili pepper is used as a food, seasoning and has been revered for its medicinal and health claims. It is very popular and is the most common spice worldwide. Capsaicin (CAP) is
a major pungent and bioactive phytochemical in chili peppers. CAP has been shown to improve
mitochondrial biogenesis and adenosine triphosphate (ATP) production. ...
Betaine Supplementation Enhances Lipid Metabolism and Improves Insulin Resistance in Mice Fed a High-Fat Diet
Abstract: Obesity is a major driver of metabolic diseases such as nonalcoholic fatty liver disease,
certain cancers, and insulin resistance. However, there are no effective drugs to treat obesity. Betaine is a nontoxic, chemically stable and naturally occurring molecule. This study shows that dietary betaine supplementation ...
b-Catenin Knockdown Affects Mitochondrial Biogenesis and Lipid Metabolism in Breast Cancer Cells
b-catenin plays an important role as regulatory hub in several cellular processes including cell adhesion, metabolism, and epithelial mesenchymal transition. This is mainly achieved by its dual role as structural component of cadherin-based adherens junctions, and as a key nuclear effector of the Wnt pathway. For this dual role, different ...
Apple procyanidins promote mitochondrial biogenesis and proteoglycan biosynthesis in chondrocytes
Apples are well known to have various benefits for the human body. Procyanidins are a class of
polyphenols found in apples that have demonstrated effects on the circulatory system and skeletal
organs. Osteoarthritis (OA) is a locomotive syndrome that is histologically characterized by cartilage degeneration associated with the impairment of ...
Anti-Fatigue Effects of Small Molecule Oligopeptides Isolated from Panax ginseng C. A. Meyer in Mice
Abstract: Panax ginseng C. A. Meyer (ginseng) is an edible and medicinal Chinese herb, which
is often used in Asian countries for physical fitness. Ginseng is reported to have a wide range
of biological activity and pharmaceutical properties. There were more studies on ginsenosides
and polysaccharides, but fewer studies on ginseng oligop...
A Critical Assessment of the Therapeutic Potential of Resveratrol Supplements for Treating Mitochondrial Disorders
Abstract: In human cells, mitochondria provide the largest part of cellular energy in the form
of adenosine triphosphate generated by the process of oxidative phosphorylation (OXPHOS).
Impaired OXPHOS activity leads to a heterogeneous group of inherited diseases for which therapeutic options today remain very limited. ...
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Iniciando mais um ano de atualizações científicas, esta edição conta com temas relevantes para agregar mais conhecimento à prática clínica de nossos leitores.
A esteatose hepática é um desequilíbrio que acomete centenas de pessoas todos os anos e está associada ao aumento da obesidade a estilos de vida não saudáveis. Trazemos, assim, ...
Iniciando mais um ano de atualizações científicas, esta edição conta com temas relevantes para agregar mais conhecimento à prática clínica de nossos leitores.
A esteatose hepática é um desequilíbrio que acomete centenas de pessoas todos os anos e está associada ao aumento da obesidade a estilos de vida não saudáveis. Trazemos, assim, uma importante revisão sobre o papel da nutrição nessa doença, ressaltando que por meio de ...
