• Nutrição e Exposição aos metais tóxicos e efeitos à saúde – Artigo 2

    Assessment of the potential health risks associated with the aluminium, arsenic, cadmium and lead content in selected fruits and vegetables grown in Jamaica A B S T R A C T Thirteen Jamaican-grown food crops − ackee (Blighia sapida), banana (Musa acuminate), cabbage (Brassica oleracea), carrot (Daucus carota), cassava (Manihot esculenta), coco (Xanthosoma sagittifolium), dasheen (Colocasia esculenta), Irish potato (Solanum tuberosum), ...
  • Nutrição e Exposição aos metais tóxicos e efeitos à saúde – Artigo 1

    A Case-Control Study of Skin Cancer and Exposure of Toxic Heavy Metals Dear Editor: The prevalence of skin cancer is increasing in Korea1. Although increased public awareness has contributed to this trend, other risk factors or mechanisms in addition to ultraviolet-exposure may be involved. It is known that exposure to heavy metals contributes to the development of skin cancers2. The main threats to human health are associated with ...
  • Nutrição e Saúde Mitocondrial – Artigo 20

    Skeletal Muscle-Specific Overexpression of PGC-1α Induces Fiber-Type Conversion through Enhanced Mitochondrial Respiration and Fatty Acid Oxidation in Mice and Pigs Abstract Individual skeletal muscles in the animal body are heterogeneous, as each is comprised of different fiber types. Type I muscle fibers are rich with mitochondria, and have high oxidative metabolisms while type IIB fibers have few mitochondria and high glycolytic ...
  • Nutrição e Saúde Mitocondrial – Artigo 19

    Sesamol Induces Human Hepatocellular Carcinoma Cells Apoptosis by Impairing Mitochondrial Function and Suppressing Autophagy Sesamol, a nutritional phenolic antioxidant compound enriched in sesame seeds, has been shown to have potential anticancer activities. This study aims at characterizing the antitumor efficacy of sesamol and unveiling the importance of mitochondria in sesamol-induced effects using a human hepatocellular carcinoma ...
  • Nutrição e Saúde Mitocondrial – Artigo 18

    Quercetin induces mitochondrial biogenesis in experimental traumatic brain injury via the PGC-1α signaling pathway Abstract: Quercetin, a dietary flavonoid used as a food supplement, has been found to have protective effect against mitochondria damage after traumatic brain injury (TBI) in mice. However, the mechanisms underlying these effects are still not well understood. The aim of the present study was to investigate the effect of ...
  • Nutrição e Saúde Mitocondrial – Artigo 17

    Pomegranate extract decreases oxidative stress and alleviates mitochondrial impairment by activating AMPK-Nrf2 in hypothalamic paraventricular nucleus of spontaneously hypertensive rats High blood pressure, or “hypertension,” is associated with high levels of oxidative stress in the paraventricular nucleus of the hypothalamus. While pomegranate extract is a known antioxidant that is thought to have antihypertensive effects, the ...
  • Nutrição e Saúde Mitocondrial – Artigo 16

    Neuroprotection by quercetin via mitochondrial function adaptation in traumatic brain injury: PGC-1a pathway as a potential mechanism Abstract The aim of this study was to investigate the neuroprotective effects of quercetin in mouse models of traumatic brain injury (TBI) and the potential role of the PGC-1a pathway in putative neuroprotection. Wild-type mice were randomly assigned to four groups: the sham group, the TBI group, the ...
  • Nutrição e Saúde Mitocondrial – Artigo 15

    Effect of Eicosapentaenoic Acid and Docosahexaenoic Acid on Myogenesis and Mitochondrial Biosynthesis during Murine Skeletal Muscle Cell Differentiation Polyunsaturated fatty acids are important nutrients for human health, especially omega-3 fatty acids such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which have been found to play positive roles in the prevention of various diseases. However, previous studies have ...