Nutrição e Hiperhomocisteinemia – Artigo 6
Tratamento dietético da hiper-homocisteinemia na doença arterial periférica
Resumo
A homocisteína está envolvida na gênese da aterosclerose e, assim, é considerada um importante e prevalente fator de risco na doença arterial periférica. O estado nutricional vitamínico deficiente, em especial do folato, é a principal causa de hiper-homocisteinemia nesses casos. Embora ainda não haja consenso sobre a dose exata e a forma de utilização do folato em suplementos e sobre adequação alimentar ou fortificação de cereais para o tratamento da hiper-homocisteinemia, diversos estudos ...
Nutrição e Hiperhomocisteinemia – Artigo 5
The Treatment of Hyperhomocysteinemia
Abstract
The unique biochemical profile of homocysteine is characterized by chemical reactivity supporting a wide range of molecular effects, and a tendency to promote oxidant stress-induced cellular toxicity. Numerous epidemiological reports have established hyperhomocysteinemia as an independent risk factor for cardiovascular disease, cerebrovascular disease, dementia-type disorders, and osteoporosis-associated fractures. Although combined folic acid and B-vitamin therapy substantially reduces homocysteine levels, results from randomized placebo-c...
Nutrição e Hiperhomocisteinemia – Artigo 4
Lowering homocysteine and modifying nutritional status with folic acid and vitamin B12 in Indian patients of vascular disease
Abstract
Hyperhomocysteinemia is more commonly associated with vascular disease in Indians than in the western populations. It is caused by genetic polymorphisms or dietary deficiencies of the B vitamins. We attempted to identify the association of hyperhomocysteinemia with vitamin B12 and folate in Indian patients of vascular disease. Homocysteine, vitamin B12 and folate levels were estimated in 100 controls and 100 patients of vascular disease.
Homocysteine ...
Nutrição e Hiperhomocisteinemia – Artigo 3
Hyperhomocysteinemia as a Risk Factor and Potential Nutraceutical Target for Certain Pathologies
Abstract
Hyperhomocysteinemia is recognized as a risk factor for several diseases, including cardiovascular and neurological conditions. Homocysteine (HCys) is a key metabolite involved in the biosynthesis andmetabolismofmethionine (Met),which plays a pivotal role in the physiological cell’s life cycle. The biochemistry of Met is finely regulated by several enzymes that control HCys concentration. Indeed, balanced activity among the enzymes is essential for the cell’s well-being, while its ...
Nutrição e Hiperhomocisteinemia – Artigo 2
Influence of Dietary Supplementation for Hyperhomocysteinemia Treatments
Abstract: Hyperhomocysteinemia is recognized as risk factor for cardiovascular and age-associated diseases. Folic acid supplementation eciently lowers plasma homocysteine (Hcy) levels, but high intake may negatively aect health because of unnatural levels of unmetabolized folic acid in the systemic circulation. Oxoproline (Oxo) provides by glutamic acid production an increase of intracellular folic acid trapping. Aim of this study was to compare the ecacy of three supplementation protocols: (1) traditional therapy ...
Nutrição e Hiperhomocisteinemia – Artigo 1
The metabolism and significance of homocysteine in nutrition and health
Abstract
An association between arteriosclerosis and homocysteine (Hcy) was first demonstrated in 1969. Hcy is a sulfur
containing amino acid derived from the essential amino acid methionine (Met). Hyperhomocysteinemia (HHcy) was
subsequently shown in several age-related pathologies such as osteoporosis, Alzheimer’s disease, Parkinson’s disease, stroke, and cardiovascular disease (CVD). Also, Hcy is associated with (but not limited to) cancer, aortic aneurysm, hypothyroidism and end renal stage disease to ...
Nutrição e Hipertrofia – Intervenção Nutricional
Associados, juntamente com os artigos do mês, vocês receberão uma cartilha resumo com as principais intervenções nutricionais da condição/ doença que é tema do mês! A cartilha resumo poderá ser utilizada como um material de apoio para o momento do atendimento nutricional, facilitando a prescrição de condutas com base nos dados mais recentes dos estudos científicos.
Nutrição e Hipertrofia – Artigo 10
Effects of β-Alanine Supplementation on Subjects Performing High-Intensity Functional Training
Abstract:
Background: β-alanine, a non-essential amino acid found in the diet and produced through nucleotide catabolism, is significant for muscle performance due to its role in carnosine synthesis. This study aims to assess the impact of a 4-week β-alanine supplementation on neuromuscular fatigue in individuals engaging in High-Intensity Functional Training (HIFT) and its subsequent effect on sports performance, distinguishing between central fatigue from the CNS and peripheral fatigue from ...
