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Instituto Brasileiro de Nutrição Funcional Respeite seus Genes!

Posts by IBNF 1532 results

Nutrição e Tireoidite de Hashimoto – Artigo 6

Improving iodine nutritional status and increasing prevalence of autoimmune thyroiditis in children ABSTRACT Objective: The objective of this study is to evaluate the link between excess iodine intake as evidenced by increased urinary iodine excretion (UIE) and autoimmune thyroiditis in children and to assess the correlation between UIE and thyroid microsomal antibody (thyroid peroxidase [TPO]) titers in children. Materials and Methods: All children with goiter between age group 6 and 12 years, were subjected to blood tests for free thyroxine, thyroid stimulating hormone, and TPO ...

Nutrição e Tireoidite de Hashimoto – Artigo 5

Hashimoto's Thyroiditis: From Genes to the Disease Abstract: Hashimoto’s thyroiditis (HT) is the most prevalent autoimmune thyroid disorder. Intrathyroidal lymphocytic infiltration is followed by a gradual destruction of the thyroid gland which may lead to subclinical or overt hypothyroidism. Biochemical markers of the disease are thyroid peroxidase and/or thyroglobulin autoantibodies in the serum which are present with a higher prevalence in females than in males and increase with age. Although exact mechanisms of aetiology and pathogenesis of the disorder are not completely ...

Nutrição e Tireoidite de Hashimoto – Artigo 4

Evaluation of Xerostomia and salivary flow rate in Hashimoto’s Thyroiditis  Abstract Background: One of the most common causes of hypothyroidism is Hashimoto´s Thyroiditis (HT). Early detection of dry mouth is critical in preserving and promoting systemic and oral health. In this study we have assessed, for the first time, salivary function and xerostomia in HT patients who have not been involved with Sjögren´s syndrome. Material and Methods: HT was diagnosed in 40 patients based on clinical findings and positive anti-thyroid peroxidase antibodies (anti-TPO). Controls, matched ...

Nutrição e Tireoidite de Hashimoto – Artigo 3

Association between Hashimoto’s thyroiditis and cholelithiasis: a retrospective cohort study in Taiwan Abstract Objective To investigate the relation of Hashimoto’s thyroiditis (HT) to cholelithiasis and cholecystectomy in a retrospective population-based study. Setting Cohort study. Participants We identified 1268 patients aged ≥20 years with HT between 2000 and 2010 as the study cohort. Primary and secondary outcome measures Patients without HT were randomly selected from a database and propensity-matched with the study cohort at a 1:4 ratio according to age, sex, ...

Nutrição e Tireoidite de Hashimoto – Artigo 2

Altered expression of CTLA-4, CD28, VDR, and CD45 mRNA in T cells of patients with Hashimoto’s thyroiditis — a pilot study Abstract Introduction: CD28/T-cell receptor (TCR)/cytotoxic T-lymphocyte antigen 4 (CTLA4) complex controls T-cell tolerance and autoimmunity in Hashimoto’s thyroiditis (HT). In addition, CD45 protein tyrosine phosphatase (PTPase) and vitamin D receptor (VDR) cooperatively interact with the TCR complex to affect autoimmune processes central to the pathogenesis of HT. Nevertheless, their role in HT aetiology has been less well established. In this study, we ...

Nutrição e Tireoidite de Hashimoto – Artigo 1

25-Hydroxyvitamin D serum level in Hashimoto’s thyroiditis, but not Graves’ disease is relatively deficient Abstract. Vitamin D is a modulator of both the innate and adaptive immune system. As vitamin D deficiency was a risk factor for some autoimmune diseases, we aimed to evaluate the serum vitamin D levels in autoimmune thyroid diseases(AITD) including Graves’ disease (GD) and Hashimoto’s thyroiditis (HT) and investigated the association between serumvitamin D levels and AITD. 175 AITD patients including 51 GD, 61 euthyroid HT (mild HT), 63 euthyroid HT patientswith hypothyro...

Nutrição e Doença Celíaca – Artigo 20

The Role of Gluten in Celiac Disease and Type 1 Diabetes Abstract: Celiac disease (CD) and type 1 diabetes (T1D) are autoimmune conditions in which dietary gluten has been proven or suggested to play a pathogenic role. In CD; gluten is established as the instigator of autoimmunity; the autoimmune process is halted by removing gluten from the diet; which allows for resolution of celiac autoimmune enteropathy and subsequent normalization of serological markers of the disease. However; an analogous causative agent has not yet been identified for T1D. Nevertheless; the role of dietary ...

Nutrição e Doença Celíaca – Artigo 19

The neurologic significance of celiac disease biomarkers ABSTRACT Objective: To report neurologic phenotypes and their etiologies determined among 68 patients with either (1) celiac disease (CD) or (2) no CD, but gliadin antibody positivity (2002–2012). Methods: Neurologic patients included both those with the CD-prerequisite major histocompatibility complex class II human leukocyte antigen (HLA)-DQ2/DQ8 haplotype, and those without. The 3 groups were as follows: group 1 (n 5 44), CD or transglutaminase (Tg)-2/deamidated gliadin immunoglobulin (Ig)A/IgG detected; group 2 (n 5 15), ...