Discussão Científica – Litíase Renal – Profª Julie Lobo – Artigo 10
Whey protein and albumin effects upon urinary risk factors
for stone formation
Abstract Protein supplements are consumed for an expected increase in muscle mass and improved exercise
performance, but as their impact on lithogenic parameters are unknown, we aimed to evaluate the effects of Whey
protein (WP) and Albumin upon the risk factors for nephrolithiasis. WP or Albumin supplements (one scoop/day)
were administered for 3 days to 18 healthy volunteers, with 1-week washout period between them. Serum and
24-h urine samples were collected at baseline and after completing each interv...
Discussão Científica – Litíase Renal – Profª Julie Lobo – Artigo 9
“Green Smoothie Cleanse” Causing Acute Oxalate Nephropathy
Oxalate nephropathy is an uncommon condition that causes acute kidney injury with the potential for progression to end-stage renal disease. Diagnosis is based on the kidney biopsy findings of abundant polarizable calcium oxalate crystals in the epithelium and lumen of renal tubules. We report a case of acute oxalate nephropathy in a 65-year-old woman, temporally associated with the consumption of an oxalate-rich green smoothie juice “cleanse” prepared from juicing oxalate-rich green leafy vegetables and fruits. Predisposing ...
Discussão Científica – Litíase Renal – Profª Julie Lobo – Artigo 8
The Efficacy of Polyunsaturated Fatty Acids as Protectors against Calcium Oxalate Renal Stone
Formation: A Review
Abstract: In the pathogenesis of hypercalciuria and hyperoxaluria, n-6 polyunsaturated fatty acids (PUFAs) have been implicated by virtue of their metabolic links with arachidonic acid (AA) and prostaglandin PGE2. Studies have also shown that n-3 PUFAs, particularly those in fish oil—eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)—can serve as competitive substrates for AA in the n-6 series and can be incorporated into cell membrane phospholipids in the latter...
Discussão Científica – Litíase Renal – Profª Julie Lobo – Artigo 7
Mediterranean diet adherence and risk of incident kidney stones
ABSTRACT
Background: Diet plays an important role in kidney stone formation. Several individual components have been associated with the risk of kidney stone formation, but there is limited evidence regarding the role of healthful dietary patterns.
Objective: To prospectively study the association between adherence to theMediterranean diet and the risk of incident kidney stones.
Methods: We conducted a longitudinal study using 3 different cohorts: the Health Professionals Follow-up Study (n=42,902 men), the Nurses’ Health ...
Discussão Científica – Litíase Renal – Profª Julie Lobo – Artigo 6
Which Diet for Calcium Stone Patients: A Real-World Approach to Preventive Care
Abstract: Kidney stone disease should be viewed as a systemic disorder, associated with or predictive of hypertension, insulin resistance, chronic kidney disease and cardiovascular damage. Dietary and lifestyle changes represent an important strategy for the prevention of kidney stone recurrences and cardiovascular damage. A full screening of risk factors for kidney stones and for cardiovascular damage should be recommended in all cases of calcium kidney stone disease, yet it is rarely performed outside of ...
Discussão Científica – Litíase Renal – Profª Julie Lobo – Artigo 5
Nutrition and Kidney Stone Disease
Abstract: The prevalence of kidney stone disease is increasing worldwide. The recurrence rate of urinary stones is estimated to be up to 50%. Nephrolithiasis is associated with increased risk of chronic and end stage kidney disease. Diet composition is considered to play a crucial role in urinary stone formation. There is strong evidence that an inadequate fluid intake is the major dietary risk factor for urolithiasis. While the benefit of high fluid intake has been confirmed, the effect of different beverages, such as tap water, mineral water, fruit ...
Discussão Científica – Litíase Renal – Profª Julie Lobo – Artigo 4
Nutritional Management of Kidney Stones (Nephrolithiasis)
The incidence of kidney stones is common in the United States and treatments for them are very costly. This review article provides information about epidemiology, mechanism, diagnosis, and pathophysiology of kidney stone formation, and methods for the evaluation of stone risks for new and follow-up patients. Adequate evaluation and management can prevent recurrence of stones. Kidney stone prevention should be individualized in both its medical and dietary management, keeping in mind the specific risks involved for each type of ...
Discussão Científica – Litíase Renal – Profª Julie Lobo – Artigo 3
Diet-Induced Low-Grade Metabolic Acidosis and Clinical Outcomes: A Review
Abstract: Low-grade metabolic acidosis is a condition characterized by a slight decrease in blood pH, within the range considered normal, and feeding is one of the main factors that may influence the occurrence of such a condition. The excessive consumption of acid precursor foods (sources of phosphorus and proteins), to the detriment of those precursors of bases (sources of potassium, calcium, and magnesium), leads to acid-base balance volubility. If this condition occurs in a prolonged, chronic way, low-grade ...
