Nutrição e Enxaqueca – Artigo 21
Riboflavin Has Neuroprotective Potential: Focus on Parkinson’s Disease and Migraine
With the huge negative impact of neurological disorders on patient’s life and society resources, the discovery of neuroprotective agents is critical and cost-effective. Neuroprotective agents can prevent and/or modify the course of neurological disorders. Despite being underestimated, riboflavin offers neuroprotective mechanisms. Significant
pathogenesis-related mechanisms are shared by, but not restricted to, Parkinson’s disease (PD) and migraine headache. Those pathogenesis-related mechanisms can ...
Nutrição e Enxaqueca – Artigo 20
Prophylactic effect of riboflavin on pediatric migraine: a randomized, double-blind, placebo-controlled trial
Abstract
Background and aim: Riboflavin may have an acceptable effect on migraine among children. This study was
carried out to determine the prophylactic effect of riboflavin on migraine in children.
Methods: This randomized clinical trial study was performed at Shahid Beheshti Hospital in Kashan, Iran from
December 2012 to February 2015. Ninety children with migraine were allocated randomly into 3 groups (placebo, low-dose and high-dose riboflavin). The outcomes (frequency, ...
Nutrição e Enxaqueca – Artigo 19
Effectiveness of riboflavin in pediatric migraine prevention
Abstract
Question The rate of migraine diagnosed among children is increasing. Is riboflavin, an alternative to
traditional pharmacologic agents, effective and safe for prevention of migraine in children?
Answer Because migraine is a very common condition in childhood and adolescence, often contributing to
substantial burden of illness, there is increased interest in alternatives to traditional pharmacologic prevention.
The expectation is that over-the-counter alternative medication will be less toxic, better tolerated, and ...
Nutrição e Enxaqueca – Artigo 18
The Use of Antioxidants in the Treatment of Migraine
Abstract: Despite numerous studies concerning the pathophysiology of migraine, the exact molecular mechanism of disturbances underlying migraine is still unknown. Furthermore, oxidative stress is considered to play a significant role in migraine pathogenesis. The notion of oxidative stress in migraine patients has been discussed for several decades. Over the past few years, among the substances that could potentially be used for migraine treatment, particular attention has been paid to the so-called nutraceutics, including antioxidants. ...
Nutrição e Enxaqueca – Artigo 17
Coenzyme Q10 supplementation for prophylaxis in adult patients with migraine—a meta-analysis
ABSTRACT
Objective: To determine the effects of coenzyme Q10 (CoQ10) for reduction in the severity, frequency of migraine
attacks and duration of headache in adult patients with migraine. Design Systematic review and meta-analysis.
Data sources Cochrane Central Register of Controlled Trials, CENTRAL, MEDLINE, EMBASE, Cumulative Index
to Nursing and Allied Health Literature (CINAHL) and Psychological Information Database (PsycINFO) from
inception till December 2019. Study selection All ...
Nutrição e Enxaqueca – Artigo 16
Therapeutic Implications of Altered Energy Metabolism in Migraine: A State-of-the-Art
Review
Abstract
Currently, the management strategies aimed at the resolution of migraine are pharmacological. Most of these therapies are known to alter the serotonin balance of the brain. Furthermore, therapies blocking the calcitonin gene-related peptide (CGRP) have also proven to be quite effective in their treatments. However, apart from being expensive, these therapies do not influence premonitory and aura symptoms. This suggests an incomplete approach and an inadequate understanding of the ...
Nutrição e Enxaqueca – Artigo 15
A combination of coenzyme Q10, feverfew and magnesium for migraine prophylaxis: a
prospective observational study
Abstract
Background: Feverfew (Tanacetum parthenium L.), magnesium and coenzyme Q10 are frequently used for migraine
prophylaxis. Supplementation with a fixed combination of these three agents (Antemig®, PiLeJe) was investigated in an observational study.
Methods: Adult patients suffering from migraine according to the criteria of the International Headache Society
were enrolled by general practitioners (≥2 migraine attacks during previous month; exclusion of chronic ...
Nutrição e Enxaqueca – Artigo 14
The Role of Magnesium in Neurological Disorders
Abstract: Magnesium is well known for its diverse actions within the human body. From a neurological standpoint, magnesium plays an essential role in nerve transmission and neuromuscular conduction. It also functions in a protective role against excessive excitation that can lead to neuronal cell death (excitotoxicity), and has been implicated in multiple neurological disorders. Due to these important functions within the nervous system, magnesium is a mineral of intense interest for the potential prevention and treatment of neurological ...
