Nutrição e esteatose hepática – Artigo 05
Quercetin reduces obesity-induced hepatosteatosis by enhancing mitochondrial oxidative metabolism via heme oxygenase-1
Abstract
Background: Obesity-induced hepatic lipid accumulation causes lipotoxicity, mitochondrial dysfunction, oxidative stress, and insulin resistance, and is implicated in non-alcoholic hepatic pathologies such as steatohepatitis and fibrosis. Heme oxygenase-1 (HO-1), an important antioxidant enzyme catalyzing the rate-limiting step in heme degradation, protects ...
Nutrição e esteatose hepática – Artigo 04
Probiotics modify tight-junction proteins in an animal model of nonalcoholic fatty liver disease
Abstract
Background: We have investigated the effects of a multispecies probiotic preparation containing a combination of probiotic bacterial genera that included Bifidobacteria, Lactobacilli and a Streptococcus in a mouse model of high-fat diet or obesity-induced liver steatosis. Methods: Three groups of C57B1/6J mice were fed either a standard chow or a high-fat diet for 20 ...
Nutrição e esteatose hepática – Artigo 03
Micronutrient Antioxidants and Nonalcoholic Fatty Liver Disease
Abstract: Nonalcoholic fatty liver disease (NAFLD) is one of the most important chronic liver diseases worldwide and has garnered increasing attention in recent decades. NAFLD is characterized
by a wide range of liver changes, from simple steatosis to nonalcoholic steatohepatitis, cirrhosis, and hepatocellular carcinoma. The blurred pathogenesis of NAFLD is very complicated and involves lipid accumulation, insulin resistance, ...
Nutrição e esteatose hepática – Artigo 02
Lack of Benefit of Early Intervention with Dietary Flax and Fish Oil and Soy Protein in Orthologous Rodent Models of Human Hereditary Polycystic Kidney Disease
Abstract
Rationale for dietary advice in polycystic kidney disease (PKD) is based in part on animal studies that have examined non-orthologous models with progressive development of cystic
disease. Since no model completely mimics human PKD, the purpose of the current studies was to examine the effects of dietary soy protein ...
Nutrição e esteatose hepática – Artigo 01
Efficacy of Resveratrol Supplementation against Non-Alcoholic Fatty Liver Disease: A Meta-Analysis of Placebo-Controlled Clinical Trials
Abstract
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease with rising prevalence. Increasing evidence has demonstrated that resveratrol, a dietary phytochemical,
is capable of attenuating NAFLD development and progression; however, results from clinical studies are inconsistent and inconclusive. Here, we conducted a ...
Nutrição e síndrome metabólica – Artigo 21
Zinc Finger 259 Gene Polymorphism rs964184 is Associated with
Serum Triglyceride Levels and Metabolic Syndrome
Metabolic syndrome (MetS) is characterized by a cluster of cardiovascular risk factors that include: abdominal
obesity, dyslipidaemia, hypertension, insulin resistance and impaired glucose tolerance. Recent genome wide
association studies have identified several susceptibility regions involved in lipid metabolism that are also
associated with MetS. We have explored the association ...
Nutrição e síndrome metabólica – Artigo 20
The Relationship between Diet Quality and Acculturation of Immigrated South Asian American Adults and Their Association with Metabolic Syndrome
Abstract
Even though the total SA American population is increasing rapidly, there is a paucity of
information on the relationship between diet quality, acculturation and health outcomes
such as Metabolic Syndrome (MetS) in the low-income South Asian (SA) sub-population.
Our goal was to examine diet quality, degree of acculturation and their ...
Nutrição e síndrome metabólica – Artigo 19
The early life nutritional environment and early life stress as potential pathways towards the metabolic syndrome in
mid-life? A lifecourse analysis using the 1958 British Birth cohort
Background: Lifecourse studies suggest that the metabolic syndrome (MetS) may be rooted in the early life
environment. This study aims to examine the pathways linking early nutritional and psychosocial exposures and the
presence of MetS in midlife.
