The Effects of High-fat-diet Combined with Chronic Unpredictable Mild Stress on Depression-like Behavior and Leptin/LepRb in Male Rats Obesity is a condition characterized by massive adipose tissue accumulation, which is usually caused by complicated genetic and environmental factors1–3. Obesity is associated with many health problems including metabolic syndrome, cardiovascular diseases and psychiatric disorders4–7. Depression is a major psychiatric disorder...
