Transglutaminases in Dysbiosis As Potential Environmental Drivers of Autoimmunity Protein-glutamine g-glutamyltransferases (transglutaminases, Tgs) belong to the class of transferases. They catalyze the formation of an isopeptide bond between the acyl group at the end of the side chain of protein- or peptide-bound glutamine residues and the first order +-amine groups of protein- or peptide-bound lysine. The Tgs are considered to be...