Agrotóxicos e efeitos à saúde – Artigo 8
Early-life chemical exposures and risk of metabolic syndrome
The global prevalence of obesity has been increasing at a staggering pace, with few
indications of any decline, and is now one of the major public health challenges worldwide. While obesity and metabolic syndrome (MetS) have historically thought to be largely driven by increased caloric intake and lack of exercise, this is insufficient to account for the observed changes in disease trends. There is now increasing evidence to suggest that exposure to synthetic chemicals in our environment may also play a key role in the etiology ...
Nutrição e Restrição de Sono – Artigo 20
A change in objective sleep duration is associated with a change in the serum adiponectin level of women with overweight or obesity undergoing weight loss intervention
Background Although the serum adiponectin level is inversely correlated to body mass index and closely associated with obesity and related diseases, neither the impact of weight loss on the adiponectin level nor other factors that might influence the adiponectin level during weight loss intervention are well documented. Objective The objective of the study is to assess the change in the serum adiponectin level during weight ...
Nutrição e Restrição de Sono – Artigo 2
Sleep Restriction Enhances the Daily Rhythm of Circulating Levels of Endocannabinoid 2-Arachidonoylglycerol
Study Objectives: Increasing evidence from laboratory and epidemiologic studies indicates that insufficient sleep may be a risk factor for obesity. Sleep curtailment results in stimulation of hunger and food intake that exceeds the energy cost of extended wakefulness, suggesting the involvement of reward mechanisms. The current study tested the hypothesis that sleep restriction is associated with activation of the endocannabinoid (eCB) system, a key component of hedonic pathways ...
Nutrição e Restrição de Sono – Artigo 10
Obese Veterans Enrolled in a Veterans Affairs Medical Center Outpatient Weight Loss Clinic Are Likely to Experience Disordered Sleep and Posttraumatic Stress
Study Objectives: This cross-sectional study aimed to characterize sleep patterns, the quality and duration of sleep, and estimate the prevalence of common sleep disorders and posttraumatic stress disorder (PTSD) in a hospital-based Veterans Affairs MOVE! (Managing Overweight Veterans Everywhere) clinic. Methods: Participants completed five instruments: the Pittsburgh Sleep Quality Index (PSQI), Smith’s Measure of Morningness/Evenin...
Nutrição e Saúde Hepática – Artigo 17
Protective effects of saffron extract and crocin supplementation on fatty liver tissue of high-fat diet-induced obese rats
Background: Saffron is the dried stigma of Crocus sativus L. flower which commonly used as a natural remedy to enhance health and even fights disease in the Middle-East and Southeast Asian countries. Methods: This study was aimed to investigate protective effect of saffron extract and crocin in fatty liver tissue of high-fat diet induced obese rats. A total of 36 healthy male Sprague Dawley rats were divided into six groups. Two groups served as controls, a normal diet ...
Chá verde e efeitos à saúde – Artigo 12
Long-Term Supplementation of Green Tea Extract Does Not Modify Adiposity or Bone Mineral Density in a Randomized Trial of Overweight and Obese Postmenopausal Women
Abstract
Background: Green tea extract (GTE) consumption has been linked to favorable changes in adiposity and bone mineral
density (BMD), although it is unknown if these effects are due to green tea catechins or caffeine. The catechol-Omethyltransferase
(COMT) genotype may also modify these associations.
Objective: We examined the impact of decaffeinated GTE on body composition (using dual-energy X-ray absorptiometry)
...
Nutrição e esteatose hepática – Artigo 05
Quercetin reduces obesity-induced hepatosteatosis by enhancing mitochondrial oxidative metabolism via heme oxygenase-1
Abstract
Background: Obesity-induced hepatic lipid accumulation causes lipotoxicity, mitochondrial dysfunction, oxidative stress, and insulin resistance, and is implicated in non-alcoholic hepatic pathologies such as steatohepatitis and fibrosis. Heme oxygenase-1 (HO-1), an important antioxidant enzyme catalyzing the rate-limiting step in heme degradation, protects against oxidative stress, inflammation, and metabolic dysregulation. Here, we demonstrate that the ...
Nutrição e síndrome metabólica – Artigo 18
Serum vitamin A status is associated with obesity and the metabolic syndrome among school-age children in
Chongqing, China
The aim of our study was to examine the association of vitamin A status with obesity and the metabolic syndrome
(MS) in school-age children in Chongqing, China. A cross-sectional study was conducted of 1,928 children aged
7~11 years from 5 schools in Chongqing, China. Body height, weight, waist circumference (WC) and blood pressure
were measured. Blood glucose, lipids and vitamin A were determined. Overall prevalences for overweight,
obesity and MS were 10.1%, 6.7% ...