Ações do Zinco na Saúde Humana – Artigo 4
Environmental exposure to zinc and copper influences sperm quality in fertile males
Introduction. The presented study was designed to investigate the associations between environmental exposure to zinc and copper and levels of the parameters of oxidative stress and antioxidant defence system and selected cytokines in the
seminal plasma of fertile males.
Materials and methods. The study population consisted of 65 fertile male volunteers from the southern region of Poland. Based on the medians of the levels of copper and zinc in seminal plasma, the study subjects were divided into 4 ...
Ações do Zinco na Saúde Humana – Artigo 1
A prospective study of dietary and supplemental zinc intake and risk of type 2 diabetes depending on genetic variation in
SLC30A8
Background: The solute carrier family 30 member 8 gene (SLC30A8) encodes a zinc transporter in the pancreatic beta cells and the major C-allele of a missense variant (rs13266634; C/T; R325W) in SLC30A8 is associated with an increased risk of type 2 diabetes (T2D). We hypothesized that the association between zinc intake and T2D may be modified by the SLC30A8 genotype.
Results: We carried out a prospective study among subjects with no history cardio-metabolic ...
Ações do Zinco na Saúde Humana – Artigo 7
Serum Copper, Zinc, and Iron Levels in Patients with Alzheimer’s Disease: A Meta-Analysis of Case-Control Studies
Background: Many publications have investigated the association between metal ions
and the risk of Alzheimer’s disease (AD), but the results were ambiguous.
Aims: The objective of this study was to assess the association between the serum
levels of metals (copper/zinc/iron) and the risk of AD via meta-analysis of case-control studies.
Methods: We screened literatures published after 1978 in the Pubmed, Embase,
Cochrane library, Web of Science and ClinicalTrials.gov. ...
Ações do Zinco na Saúde Humana – Artigo 12
Zinc in Pancreatic Islet Biology, Insulin Sensitivity, and Diabetes
About 20 chemical elements are nutritionally essential for humans with defined molecular functions. Several essential and nonessential biometals are either functional nutrients with antidiabetic actions or can be diabetogenic. A key question remains whether changes in the metabolism of biometals and biominerals are a consequence of diabetes or are involved in its etiology. Exploration of the roles of zinc (Zn) in this regard is most revealing because 80 years of scientific discoveries link zinc and diabetes. In pancreatic ...
Ações do Zinco na Saúde Humana – Artigo 18
Zinc Supplementation Increases Procollagen Type 1 Amino-Terminal Propeptide in Premenarcheal Girls: A Randomized
Controlled Trial
Background: Data have shown that healthy children and adolescents have an inadequate intake of zinc, an essential nutrient for growth. It is unclear whether zinc supplementation can enhance bone health during this rapid period of growth
and development.
Objective: The primary aim of this study was to determine the effect of zinc supplementation on biochemical markers of
bone turnover and growth in girls entering the early stages of puberty. The secondary aim ...
Diabetes e nutrição – Artigo 2
Altered Concentrations of Copper, Zinc, and Iron are Associated With Increased Levels of Glycated Hemoglobin in Patients With Type 2 Diabetes Mellitus and Their First-Degree Relatives
The altered levels of some essential trace elements and antioxidant minerals have been observed in diabetic patients. Objectives: The aim of the present study was to compare the concentrations of essential trace elements, copper (Cu), zinc (Zn), and iron (Fe) in the serum of patients who have type 2 diabetes mellitus (T2DM) with those of their non-diabetic first-degree relatives (FDR) and control subjects. The ...
