Nutrição e Saúde da Tireoide – Artigo 14
Radioiodine-induced oxidative stress in patients with differentiated thyroid carcinoma and effect of supplementation with vitamins C and E and selenium (antioxidants)
Objective: The objective of this study, in addition to confirming that therapy with 131I causes oxidative stress, was to evaluate the effect of supplementation with vitamins C and E and selenium on this phenomenon by measuring plasma 8-epi-PGF2a, a marker of lipid peroxidation. Subjects and methods: Forty patients with thyroid cancer submitted to thyroidectomy, who received 3.7 GBq 131I after levothyroxine withdrawal, were ...
Nutrição e Saúde da Tiroide – Artigo 17
Thyroid Hormone Receptor Beta in the Ventromedial Hypothalamus Is Essential for the Physiological Regulation of Food Intake and Body Weight
Energy homeostasis is regulated by neurotransmitters and by humoral factors including thyroid hormones, which act within the hypothalamus and systemically to regulate food intake (Coppola et al., 2007, Coll et al., 2007) and energy expenditure (Kim, 2008). The effects of the active form of thyroid hormone, 3,5,3′-Ltriiodothyronine (T3), are mediated by two thyroid hormone receptors (TRα and TRβ), encoded by Thraand Thrb, respectively (Brent, 2012). ...
Nutrição e Saúde da Tiroide – Artigo 16
The relationship between iodine intake and the risk of thyroid cancer A meta-analysis
Thyroid cancer (TC) is the most common malignancy of the endocrine system. The relationship between iodine intake and TC risk is controversial always. We aim to figure out the relationship between iodine intake and TC using meta-analysis. Literature research in MEDLINE, Embase, China National Knowledge Infrastructure, and China BioMedicine was performed up to April 2016, searched for relevant case–control and cohort studies. The effect of iodine consumption on the risk of TC was assessed using the pooled ...
Nutrição e Saúde da Tireoide – Artigo 7
Does Time of Sampling or Food Intake Alter Thyroid Function Test?
Context: A common question from most patients or laboratories is whether blood sample for thyroid‑stimulating hormone (TSH) and free T4 (fT4) needs to be collected in a fasting state and whether time of the day when sample is collected matters. Aims: The aim of the study was to study the impact of the time of day and food intake on levels of TSH and fT4. Settings and Design: Cross‑sectional prospective data collection. Subjects and Methods: We prospectively collected data from 52 volunteers who were not known to have any ...
Nutrição e Saúde da Tireoide – Artigo 4
A PRISMA-compliant systematic review and meta-analysis of the relationship between thyroid disease and different levels of iodine intake in mainland China
Background: Low-iodine intake has historically been an issue in China, causing widespread iodine deficiency diseases (IDD). China started to introduce universal salt iodization in 1995, but reports of increased thyroid disease are a concern and appropriate levels of iodine intake must be considered. Objective: To assess the prevalence of thyroid disease with different urinary iodine concentrations (UICs) in the general population of those ...
Nutrição e Saúde da Tireoide – Artigo 8
Effects of Vitamin D deficiency treatment on metabolic markers in Hashimoto thyroiditis patients
Scientists predict epidemic of type 2 diabetes in near future.[1] Diabetes has high morbidity, mortality, and economic burden on society, the increase in cost is due to its complications and complexity of care. Type 2 diabetes occurs in genetically susceptible persons who are exposed to a number of environmental factors. Vitamin D deficiency might be an environmental risk factor since Vitamin D receptor is present in β-cells of pancreas and the 1-α hydroxylase enzyme which converts 25- hydrox...
Nutrição e Saúde da Tireoide – Artigo 9
Insufficient documentation for clinical efficacy of selenium supplementation in chronic autoimmune thyroiditis, based on a systematic review and meta-analysis
By a systematic review and meta-analysis to investigate clinically relevant effects of selenium supplementation in patients with chronic autoimmune thyroiditis. Controlled trials in adults (≥18 years) with autoimmune thyroiditis, comparing selenium with or without levothyroxine substitution, versus placebo and/or levothyroxine substitution, were eligible for inclusion. Identified outcomes were serum thyrotropin (thyroid stimulating ...
Nutrição e Saúde da Tiroide – Artigo 15
Selenium supplementation could restore euthyroidism in subclinical hypothyroid patients with autoimmune thyroiditis
Intriduction: The thyroid is an organ with one of the highest selenium concentrations, containing many selenoproteins implicated in thyroid hormone metabolism. Treatment with levothyroxine has been recommended for all subclinical hypothyroid patients with TSH levels > 10 mU/L, whereas for those with TSH < 10 mU/L treatment remains controversial. Aim: A randomised controlled prospective study was performed to investigate the effects of Se treatment on patients with ...
