Nutrição e Osteoporose – Artigo 2
Associations between ERα/β gene polymorphisms and osteoporosis susceptibility and bone mineral density in postmenopausal women: a systematic review and meta-analysis
Abstract
Background: Many studies have reported associations between estrogen receptor (ER) gene polymorphisms and
postmenopausal osteoporosis (PMOP) risk and bone mineral density (BMD), but the results are controversial. The
aim of the present meta-analysis is to verify the association between ERα and ERβ gene polymorphisms and
osteoporosis susceptibility and BMD in postmenopausal women.
Methods: PubMed, EMBASE, ...
Nutrição e Osteoporose – Artigo 1
ASSESSMENT OF DIFFERENCES IN NUTRIENTS CONSUMPTION IN WOMEN DIAGNOSED WITH OSTEOPOROSIS AS COMPARED TO A HEALTHY CONTROL GROUP
ABSTRACT
Background. Osteoporosis is a condition that has been much more frequent for women, which is related to menopause and to their lower bone mineral density (BMD). Inappropriate diet is among the development factors of the disease.
Objective. To assess differences in consumption of particular nutrients among women with and without osteoporosis diagnosed.
Material and Methods. The study was conducted in 2013 in a group of 100 women aged 51-70, using a ...
Nutrição e HIV – Artigo 20
Vitamin D Deficiency and Metabolism in HIV-Infected and HIV-Uninfected Men in the Multicenter
AIDS Cohort Study
Abstract
We evaluated associations of serum 25-hydroxyvitamin D (25[OH]D) and 1,25-dihydroxyvitamin D (1,25[OH]2D) levels in a cohort of HIV-infected and HIV-uninfected men at risk for infection in the United States. Stored samples collected between 1999 and 2008 were tested for vitamin D metabolites between 2014 and 2015. Vitamin D deficiency was defined as a serum concentration of 25[OH]D <20 ng/ml. Multivariate models were used to assess associations of various ...
Nutrição e HIV – Artigo 19
Vitamin D levels and their impact on mineral metabolism in HIV infected patients: an exploratory study
Summary
Vitamin D has immunomodulating properties. The nuclear receptor for vitamin D is expressed in several immune cells, which convert 25-hydroxyvitamin D (25OHD) to the active form 1,25 hydroxyvitamin D [1,25(OH)2 D].
Under conditions of infection, 1,25(OH)2 D promotes production of cathelicidin (an antimicrobial peptide) in
monocytes and activated macrophages. In vitro studies have shown the ability of cathelicidin to inhibit replication of human immunodeficiency virus (HIV-1) ...
Nutrição e HIV – Artigo 18
Vitamin A supplements for reducing mother-to-child HIV transmission (Review)
A B S T R A C T
Background: Strategies to reduce the risk of mother-to-child transmission of the human immunodeficiency virus (HIV) include lifelong antiretroviral therapy (ART) for HIV-positive women, exclusive breastfeeding from birth for six weeks plus nevirapine or replacement feeding plus nevirapine from birth for four to six weeks, elective Caesarean section delivery, and avoiding giving children chewed food. In some settings, these interventions may not be practical, feasible, or affordable. Simple, ...
Nutrição e HIV – Artigo 17
Vitamin A and D deficiencies associated with incident tuberculosis in HIV-infected patients initiating antiretroviral therapy in multinational case-cohort study
Abstract
Introduction—Numerous micronutrients have immunomodulatory roles that may influence risk of tuberculosis (TB), but the association between baseline micronutrient deficiencies and incident TB after antiretroviral (ART) initiation in HIV-infected individuals is not well characterized.
Methods—We conducted a case-cohort study (n=332) within a randomized trial comparing three ART regimens in 1571 HIV treatment-n...
Nutrição e HIV – Artigo 16
The mTOR complex controls HIV Latency
SUMMARY
A population of CD4 T lymphocytes harboring latent HIV genomes can persist in patients on antiretroviral therapy, posing a barrier to HIV eradication. To examine cellular complexes controlling HIV latency, we conducted a genome-wide screen with a pooled ultracomplex shRNA library and in vitro system modeling HIV latency and identified the mTOR complex as a modulator of HIV latency. Knockdown of mTOR complex subunits or pharmacological inhibition of mTOR activity suppresses reversal of latency in various HIV-1 latency models and HIV-infe...
Nutrição e HIV – Artigo 15
The Interaction between HIV and Intestinal Helminth Parasites Coinfection with Nutrition among Adults in KwaZulu-Natal, South Africa
In South Africa few studies have examined the effects of the overlap of HIV and helminth infections on nutritional status. This cross-sectional study investigated the interaction between HIV and intestinal helminths coinfection with nutritional status among KwaZulu-Natal adults. Participants were recruited from a comprehensive primary health care clinic and stratified based on their HIV, stool parasitology, IgE, and IgG4 results into four groups: the ...
