year : 2019 242 results

Nutrição e Esteatose Hepática não alcoólica – Artigo 3

Dietary and Pharmacological Treatment of Nonalcoholic Fatty Liver Disease  Abstract: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the developed world. Simple hepatic steatosis is mild, but the coexistence of steatohepatitis (NASH) and fibrosis increases the risk of hepatocellular carcinoma. Proper dietary and pharmacological treatment is essential for preventing NAFLD progression. The first-line treatment should include dietary intervention and increased physical activity. The diet should be based on the food pyramid, with a choice of products ...

Nutrição e Esteatose Hepática não alcoólica – Artigo 2

Curcumin Ameliorates Nonalcoholic Fatty Liver Disease through Inhibition of O-GlcNAcylation Abstract: The cause of progression to non-alcoholic fatty liver disease (NAFLD) is not fully understood. In the present study, we aimed to investigate how curcumin, a natural phytopolyphenol pigment, ameliorates NAFLD. Initially, we demonstrated that curcumin dramatically suppresses fat accumulation and hepatic injury induced in methionine and choline-deficient (MCD) diet mice. The severity of hepatic inflammation was alleviated by curcumin treatment. To identify the proteins involved in the ...

Nutrição e Esteatose Hepática não alcoólica – Artigo 1

Chitosan Oligosaccharide Attenuates Nonalcoholic Fatty Liver Disease Induced by High Fat Diet through Reducing Lipid Accumulation, Inflammation and Oxidative Stress in C57BL/6 Mice Abstract: Nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease closely associated with metabolic syndrome, but there are no validated pharmacological therapies. The aim of this study was to investigate the effect of chitosan oligosaccharide (COS) on NAFLD. Mice were fed either a control diet or a high-fat diet (HFD) with or without COS (200 or 400 mg/kg body weight ...

Nutrição e Diabetes Mellitus I – Artigo 20

The Effects of Vitamin D Supplementation in Newly Diagnosed Type 1 Diabetes Patients: Systematic Review of Randomized Controlled Trials Abstract AIM: The aim of this study was to examine the effects of vitamin D supplementation in patients newly diagnosed with type 1 diabetes (T1D) assessed by insulin needs and changes in glycemic indices, as evidenced by randomized controlled trials (RCTs). METHODS: A total of 7 RCTs were retrieved from PubMed/Medline and EBSCO databases by MeSH term search, and were reviewed systematically. The RCTs included examined the effects of alphacalci...

Nutrição e Diabetes Mellitus I – Artigo 19

Specific Nuclear Magnetic Resonance Lipoprotein Subclass Profiles and Central Arterial Stiffness in Type 1 Diabetes Mellitus: A Case Control Study Abstract: Background: Dyslipidemia has been associated with vascular complications of type 1 diabetes mellitus (T1DM). We examined the proton nuclear magnetic resonance (NMR)-assessed lipoprotein subclass profilesin subjectswith T1DM comparedwith those of healthy subjects and assessed the potential relationship of these profiles with arterial stiffness. Methods: Eighty-four participants with T1DM of at least 10 years duration and no ...

Nutrição e Diabetes Mellitus I – Artigo 18

Resveratrol attenuates reproductive alterations in type 1 diabetes-induced rats SUMMARY The progression of diabetes mellitus leads to several complications including overproduction of reactive oxygen species and reproductive alterations. As resveratrol (RES) is a powerful anti-oxidant and an anti-apoptotic compound, we hypothesized that side effects of type-1 diabetes (DM1) on male reproduction could be reduced by the RES treatment. Eighty-four prepubertal male rats were distributed into seven groups: shamcontrol (SC), RES-treated (R), resveratrol-vehicle-treated (RV), diabetic (D), ...

Nutrição e Diabetes Mellitus I – Artigo 17

Micronutrient Intake in a Cohort of Italian Adults with Type 1 Diabetes: Adherence to Dietary Recommendations Micronutrients are of fundamental importance in maintaining health status. However, data on their dietary intake are few particularly in persons with diabetes. The aim of this study was to evaluate in adults with type 1 diabetes (T1DM) attending a tertiary-level diabetes center in Southern Italy the intake of micronutrients (both vitamins and minerals) and the adherence to recommendations. Seven-day food records of 60 T1DM patients were analyzed. Micronutrient intake was ...

Nutrição e Diabetes Mellitus I – Artigo 16

Medical Nutrition Therapy in Type 1 Diabetes Mellitus Introduction T1 diabetes mellitus (T1DM) is a common and chronic endocrine disorder in young adolescents. It contributes to 5%–10% of total diabetes population.[1] T1DM is the 2nd most common chronic disease in children in India with an annual incidence of 3 cases/year/1 lakh (IDF 7th edition). With the aim of addressing the relative scarcity of information on youth onset diabetes in India, the Indian Council of Medical Research (ICMR) established “the Registry of People with Diabetes with Young Age at Onset (YDR).” ...