Association between Hashimoto’s thyroiditis and cholelithiasis: a retrospective cohort study in Taiwan
Abstract
Objective To investigate the relation of Hashimoto’s thyroiditis (HT) to cholelithiasis and cholecystectomy in a
retrospective population-based study. Setting Cohort study. Participants We identified 1268 patients aged ≥20 years
with HT between 2000 and 2010 as the study cohort.
Primary and secondary outcome measures ...
Altered expression of CTLA-4, CD28, VDR, and CD45 mRNA in T cells of patients with Hashimoto’s thyroiditis — a pilot study
Abstract
Introduction: CD28/T-cell receptor (TCR)/cytotoxic T-lymphocyte antigen 4 (CTLA4) complex controls T-cell tolerance and autoimmunity in Hashimoto’s thyroiditis (HT). In addition, CD45 protein tyrosine phosphatase (PTPase) and vitamin D receptor (VDR) cooperatively interact with the TCR complex to ...
25-Hydroxyvitamin D serum level in Hashimoto’s thyroiditis, but not Graves’ disease is relatively deficient
Abstract. Vitamin D is a modulator of both the innate and adaptive immune system. As vitamin D deficiency was a risk factor for some autoimmune diseases, we aimed to evaluate the serum vitamin D levels in autoimmune thyroid diseases(AITD) including Graves’ disease (GD) and Hashimoto’s thyroiditis (HT) and investigated the ...
The Role of Gluten in Celiac Disease and Type 1 Diabetes
Abstract: Celiac disease (CD) and type 1 diabetes (T1D) are autoimmune conditions in which dietary gluten has been proven or suggested to play a pathogenic role. In CD; gluten is established as the instigator of autoimmunity; the autoimmune process is halted by removing gluten from the diet; which allows for resolution of celiac autoimmune enteropathy and subsequent normalization of ...
The neurologic significance of celiac disease biomarkers
ABSTRACT
Objective: To report neurologic phenotypes and their etiologies determined among 68 patients with either (1) celiac disease (CD) or (2) no CD, but gliadin antibody positivity (2002–2012).
Methods: Neurologic patients included both those with the CD-prerequisite major histocompatibility complex class II human leukocyte antigen (HLA)-DQ2/DQ8 haplotype, and those without....
Screening for celiac disease in poorly controlled type 2 diabetes mellitus: worth it or not?
Abstract
Background: Recent studies have demonstrated that immune factors might have a role in the pathophysiology of
insulin resistance and type 2 diabetes mellitus (T2DM). Inappropriate glycemic control in patients with T2DM is an
important risk factor for the occurrence of diabetes complications. The prevalence of celiac disease (CD) is high ...
Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease
Abstract
Viral infections have been proposed to elicit pathological processes leading to the initiation of T helper 1 (TH1) immunity against dietary gluten and celiac disease (CeD). To test this hypothesis and gain insights into mechanisms underlying virus-induced loss of tolerance to dietary antigens, we developed a viral infection ...
Refractory celiac disease and EATL patients show severe malnutrition and malabsorption at diagnosis
Summary Background & aims: Refractory celiac disease type II (RCDII) and EATL (Enteropathy Associated T-cell Lymphoma) are (pre)malignant complications of celiac disease (CD). Data on malnutrition and intestinal absorption is lacking in these patients. Therefore, the aim of the study is to comprehensively assess nutritional status and ...
