Differential Effects of Cream, Glucose, and Orange Juice on Inflammation, Endotoxin, and the Expression of Toll-Like Receptor-4 and Suppressor of Cytokine Signaling-3
OBJECTIVE — We have recently shown that a high-fat high-carbohydrate (HFHC) meal induces an increase in plasma concentrations of endotoxin (lipopolysaccharide [LPS]) and the expression of Toll-like receptor-4 (TLR-4) and suppresser of cytokine signaling-3 (SOCS3) in mononuclear cells (MNCs) in addition to oxidative stress and cellular inflammation. Saturated fat and carbohydrates, components of the HFHC meal, known to ...
Sleep Duration and All-Cause Mortality: A Systematic Review and Meta-Analysis of Prospective Studies
Background: Increasing evidence suggests an association between both short and long duration of habitual sleep with adverse health outcomes.
Objectives: To assess whether the population longitudinal evidence supports the presence of a relationship between duration of sleep and allcause mortality, to investigate both short and long sleep duration and to obtain an estimate of the risk.
Methods: We performed a systematic search of publications using MEDLINE (1966-2009), EMBASE (from 1980), ...
Mechanisms of Disease: oxidative stress and inflammation in the pathogenesis of hypertension
SUMMARY
Animal studies have shown that oxidative stress and renal tubulointerstitial inflammation are associated with, and have major roles in, the pathogenesis of hypertension. This view is supported by the observations that alleviation of oxidative stress and renal tubulointerstitial inflammation reduce arterial pressure in animal models. Conversely,
hypertension has been shown to cause oxidative stress and inflammation in renal and cardiovascular tissues in experimental animals. Taken ...
Inflammatory Markers and Loss of Muscle Mass (Sarcopenia) and Strength
ABSTRACT
PURPOSE: The objective of this study was to investigate whether high levels of serum interleukin (IL)-6, C-reactive protein (CRP), and 1-antichymotrypsin (ACT) were associated with the loss of muscle strength or muscle mass (sarcopenia) in older persons.
SUBJECTS: The study included 986 men and women of the Longitudinal Aging Study Amsterdam, with a mean age of 74.6 years (standard deviation 6.2).
METHODS: Grip strength (n 986) and appendicular muscle mass (n 328, using dual-energy x-ray absorptiometry) ...
The anti-inflammatory effect of exercise
Petersen, Anne Marie W., and Bente Klarlund Pedersen. The anti-inflammatory effect of exercise. J Appl Physiol 98: 1154 –1162, 2005; doi:10.1152/japplphysiol. 00164.2004.—Regular exercise offers protection against all-cause mortality, primarily by protection against cardiovascular disease and Type 2 diabetes mellitus. The latter disorders have been associated with chronic low-grade systemic inflammation reflected by a two- to threefold elevated level of several cytokines. Adipose tissue contributes to the production of TNF-, which is reflected ...
C-Reactive Protein Levels and Outcomes after Statin Therapy
Abstract
Background
Statins lower the levels of low-density lipoprotein (LDL) cholesterol and C-reactive protein (CRP). Whether this latter property affects clinical outcomes is unknown.
Methods
We evaluated relationships between the LDL cholesterol and CRP levels achieved after treatment with 80 mg of atorvastatin or 40 mg of pravastatin per day and the risk of recurrent myocardial infarction or death from coronary causes among 3745 patients with acute coronary syndromes.
Results
Patients in whom statin therapy resulted ...
Associados,A partir de agora, juntamente com os artigos do mês, vocês receberão uma cartilha resumo com as principais intervenções nutricionais da condição/ doença que é tema do mês! A cartilha resumo poderá ser utilizada como um material de apoio para o momento do atendimento nutricional, facilitando a prescrição de condutas com base nos dados mais recentes dos estudos científicos.
Consumo alimentar dos portadores de Doença Hepática Gordurosa Não Alcoólica: comparação entre a presença e a ausência de Esteatoepatite Não Alcoólica e Síndrome Metabólica
ObjetivoO objetivo desse estudo foi avaliar o consumo alimentar de portadores de Doença Hepática Gordurosa Não Alcoólica, comparar com as recomendações nutricionais diárias e analisar a correlação da dieta com a presença de Síndrome Metabólica e com a gravidade da doença, uma vez que estudos sobre os hábitos alimentares dos portadores de Doença Hepática Gordurosa Não Alcoólica ainda são ...
